860081P

Avanti

Egg Lyso PE

L-α-lysophosphatidylethanolamine (Egg, Chicken), powder

CAS Number:
NACRES:
NA.25

assay

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (860081P-10mg)
pkg of 1 × 100 mg (860081P-100mg)
pkg of 1 × 25 mg (860081P-25mg)

manufacturer/tradename

Avanti Polar Lipids 860081P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O

General description

Phosphatidylethanolamine is a phospholipid and is bound to the biological membranes.

Application

Egg Lyso PE is suitable for use:
  • in the activation of lysophospholipid of human transforming growth factor β1(TGF-β1)
  • in determining the influence of lysoPE on binding of class II MHC molecules to peptides containing a photoreactive compound
  • to check its effect on catherin mediated endocytosis(CME) in breast cancer SUM159 cells

Biochem/physiol Actions

Phosphatidylethanolamine has a tendency of binding to proteins and forming a complex of phosphatidylethanolamine-binding protein (PEBP).

Packaging

5 mL Amber Glass Screw Cap Vial (860081P-25mg)
5 mL Amber Glass Screw Cap Vial (860081P-100mg)
5 mL Amber Glass Screw Cap Vial (860081P-10mg)

storage_class_code

13 - Non Combustible Solids

Certificate of Analysis

Certificate of Origin

Lysophospholipid regulates release and activation of latent TGF-beta1 from chondrocyte extracellular matrix
Gay I, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1684(1-3), 18-28 (2004)
Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction
Banfield M J, et al.
Structure, 6(10), 1245-1254 (2017)
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Ailte I, et al.
Traffic, 18(3), 176-191 (2017)
Phospholipids enhance the binding of peptides to class II major histocompatibility molecules
Roof R W, et al.
Proceedings of the National Academy of Sciences of the USA, 87(5), 1735-1739 (1990)
Phosphatidylcholine?s functions beyond that of a membrane brick
Furse S and De Kroon AIPM
Molecular Membrane Biology, 32(4), 117-119 (2015)

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