C24 Ceramide has long acyl chain length of 24 carbon units.
C24 Ceramide (d18:1/24:0) has been used:
in the generation of small unilamellar vesicles
as an internal standard in liquid chromatography-mass spectrometry for ceramide quantification from rat samples
to test its effect on mitochondrial stress response in worms
C24 ceramide induces mitochondrial stress response. Its levels are depleted in coronary artery disease (CAD). However, elevated ceramide levels is observed in Alzheimer′s disease. C24 is synthesized during stress. It mediates spontaneous neutrophil death.
Journal of leukocyte biology, 81(6), 1477-1486 (2007-03-03)
Neutrophils rapidly undergo spontaneous apoptosis following their release from the bone marrow. Although central to leukocyte homeostasis, the mechanisms that regulate neutrophil apoptosis remain poorly understood. We show here that apoptosis of cultured neutrophils is preceded by a substantial increase
Ceramides and sphingomyelinases in senile plaques
Panchal M, et al.
Neurobiology of Disease, 65, 193-201 (2014)
Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides
Kauhanen D, et al.
Analytical and Bioanalytical Chemistry, 408(13), 3475-3483 (2016)
Liposome Preparation for the Analysis of Lipid-Receptor Interaction and Efferocytosis
Voss OH, et al.
Current Protocols in Immunology, 120(1), 14-44 (2018)
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