All Photos(1)

870314C

Avanti

18:1 DGS

1,2-dioleoyl-sn-glycero-3-succinate, chloroform

Empirical Formula (Hill Notation):
C43H76O8
CAS Number:
Molecular Weight:
721.06
NACRES:
NA.25

packaging

pkg of 1 × 2.5 mL (870314C-25mg)
pkg of 2 × 4 mL (870314C-200mg)

concentration

10 mg/mL (870314C-25mg)
25 mg/mL (870314C-200mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COC(CCC(O)=O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

General description

18:1 DGS or 1,2-dioleoyl-sn-glycero-3-succinate (DOSG) is a non-phospholipid. This lipid contains double oleoyl chains and all of this chains form stable fluidic bilayers.

Application

1,2-dioleoyl-sn-glycero-3-succinate (DOSG) or 18:1 DGS has been used in liposome preparation.

Packaging

5 mL Clear Glass Sealed Ampule (870314C-25mg)
5 mL Clear Glass Sealed Ampule (870314C-200mg)

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificate of Analysis

Certificate of Origin

Delivery of superoxide dismutase to pulmonary epithelium via pH-sensitive liposomes
Briscoe P, et al.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 268(3), L374-L380 (1995)
Lipid-dependent gating of a voltage-gated potassium channel
Zheng H, et al.
Nature Communications, 2(3), 250-250 (2011)
Sungsoo Lee et al.
Journal of visualized experiments : JoVE, (77), e50436-e50436 (2013-07-31)
To study the lipid-protein interaction in a reductionistic fashion, it is necessary to incorporate the membrane proteins into membranes of well-defined lipid composition. We are studying the lipid-dependent gating effects in a prototype voltage-gated potassium (Kv) channel, and have worked...

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