878115P

Avanti

C16-04:0 PC

1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine, powder

Empirical Formula (Hill Notation):
C28H58NO7P
CAS Number:
Molecular Weight:
551.74
NACRES:
NA.25
Pricing and availability is not currently available.

form

powder

packaging

pkg of 1 × 5 mg (878115P-5mg)

mfr. no.

Avanti Polar Lipids, 878115P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O-P(OCCN+(C)(C)C)(OCC@(H)(OC(CCC)=O)COCCCCCCCCCCCCCCCC)=O

General description

C16-04:0 PC, also known as 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine (butanoyl-PAF), is a platelet-activating factor (PAF) analog belonging to the class of bioactive lipids. It is produced non-enzymatically in the oxidized-low density lipoprotein (Ox-LDL) particle. Butanoyl-PAF contains ether-linked hexadecyl chain at the sn-1 position and a butyryl group at the sn-2 position. It is mostly produced in body during high oxidative stress. This lipid mediator acts as a pro-inflammatory agent.

Application

C16-04:0 PC or 1-O-hexadecyl-2-butyryl-sn-glycero-3-phosphocholine is suitable to study its physicochemical properties and its association with peptides derived from the C-terminal domains of human apolipoprotein E.

Packaging

5 mL Clear Glass Sealed Ampule (878115P-5mg)

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Certificate of Analysis
Certificate of Origin
Sunil A Nankar et al.
Biochimie, 95(6), 1196-1207 (2013-02-05)
Apolipoprotein-derived peptides are promising candidates for the treatment of various inflammatory conditions and the main mechanism proposed for the protective action of these peptides includes binding to pro-inflammatory lipid mediators with high affinity and facilitating their sequestration/metabolism/clearance in the body....

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