MilliporeSigma
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880150P

Avanti

14:0 PEG2000 PE

Avanti Polar Lipids 880150P, powder

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Synonym(s):
1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)
CAS Number:
474922-82-2
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 g (880150P-1g)
pkg of 1 × 200 mg (880150P-200mg)
pkg of 1 × 25 mg (880150P-25mg)
pkg of 1 × 500 mg (880150P-500mg)

manufacturer/tradename

Avanti Polar Lipids 880150P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[NH4+]

General description

14:0 PEG2000 PE, also called as 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DMPE-PEG2000), is a polyethylene glycol (PEG)-phospholipid conjugate. It belongs to a group of polymerizable lipids. Incorporation of DMPE-PEG in the vesicle formulation stops aggregation of vesicles upon peptide addition.

Application

14:0 PEG2000 PE or 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in: giant vesicles preparation, lipid nanoparticle (LNP) formulation, unilamellar liposomes preparation for small-angle X-ray scattering (SAXS) experiments

Packaging

5 mL Amber Glass Screw Cap Vial (880150P-25mg)
20 mL Clear Glass Screw Cap Vial (880150P-1g)
5 mL Amber Glass Screw Cap Vial (880150P-200mg)
20 mL Clear Glass Screw Cap Vial (880150P-500mg)

Storage Class Code

13 - Non Combustible Solids

Certificate of Analysis

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Certificate of Origin

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Josefine Eilsø Nielsen et al.
Biochimica et biophysica acta. Biomembranes, 1861(7), 1355-1364 (2019-04-13)
The naturally occurring peptide indolicidin from bovine neutrophils exhibits strong biological activity against a broad spectrum of microorganisms. This is believed to arise from selective interactions with the negatively charged cytoplasmic lipid membrane found in bacteria. We have investigated the
L Limozin et al.
The European physical journal. E, Soft matter, 10(4), 319-330 (2004-03-12)
We studied the formation of actin scaffolds in giant vesicles of dimyristoylphosphatidylcholine (DMPC). Polymerization of actin was induced at low ionic strength through ionophore-mediated influx of Mg2+ (2 mM). The spatial organization of the filamentous actin was visualized by confocal
Pedro P G Guimaraes et al.
Journal of controlled release : official journal of the Controlled Release Society, 316, 404-417 (2019-11-05)
Messenger RNA (mRNA) has recently emerged as a promising class of nucleic acid therapy, with the potential to induce protein production to treat and prevent a range of diseases. However, the widespread use of mRNA as a therapeutic requires safe
Dominique Leboeuf et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 28(4), 1092-1104 (2020-02-24)
The N-degron pathway is an emerging target for anti-tumor therapies, because of its capacity to positively regulate many hallmarks of cancer, including angiogenesis, cell proliferation, motility, and survival. Thus, inhibition of the N-degron pathway offers the potential to be a
Abdullah Lone et al.
Molecules (Basel, Switzerland), 24(24) (2019-12-19)
The increasing emergence of multi-drug resistant bacteria is a serious threat to public health worldwide. Antimicrobial peptides have attracted attention as potential antibiotics since they are present in all multicellular organisms and act as a first line of defence against

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