880151P

DMG-PEG 2000

Avanti Polar Lipids

• Synonym(s): 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
• Empirical Formula (Hill Notation): C₁₂₂H₂₄₂O₅₀
• CAS Number: 1397695-86-1
• Molecular Weight: 2509.20
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 g (880151P-1G); pkg of 1 × 5 g (880151P-5G)
• manufacturer/tradename: Avanti Polar Lipids
• application(s): advanced drug delivery
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O=C(CCCCCCCCCCCCC)OCC(OC(CCCCCCCCCCCCC)=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

Description

General description

Dimyristoyl glycerol (DMG) molecule associates with membrane similar to phospholipids.

Structure, molecular formula and formula weight are representative of the average polymer length of the material.

Application

DMG-PEG 2000 is suitable for use in the preparation of lipid nanoparticle for microRNA and short interfering RNA delivery.

Biochem/physiol Actions

Dimyristoyl glycerol (DMG) − polyethyleneglycol (PEG) 2000 is used for liposome preparation for anticancer drug delivery studies for hepatocellular, gastrointestinal, neuroendocrine and adrenocortical carcinoma. It is also used in lipid nanoparticle preparation for siRNA (small interfering RNA) delivery.

Packaging

20 mL Clear Glass Screw Cap Vial (880151P-1G)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (880151P-5G)

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable