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880200P

Avanti

16:0 PEG5000 PE

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (ammonium salt), powder

CAS Number:
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 1 g (880200P-1g)
pkg of 1 × 200 mg (880200P-200mg)
pkg of 1 × 25 mg (880200P-25mg)
pkg of 1 × 500 mg (880200P-500mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC([(OCH2CH2)113OCH3])=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

General description

16:0 PEG5000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 (DPPE-PEG 5000), is a mPEG phospholipid conjugate. Poly(ethylene glycol) (PEG)-based liposomal formulations are widely used in preparation of biocompatible self-assembled drug-delivery systems. These systems have an ability to escape the recognition and uptake by cells in the immune system at the same time it extends the residence time of the liposomes and allows continuous drug release into the targeted cells.

Application

16:0 PEG5000 PE or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in preparation of lipid bilayer. It has also been used in liposome preparation.

Packaging

5 mL Amber Glass Screw Cap Vial (880200P-200mg)
5 mL Amber Glass Screw Cap Vial (880200P-25mg)
20 mL Clear Glass Screw Cap Vial (880200P-1g)
20 mL Clear Glass Screw Cap Vial (880200P-500mg)

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 3

Certificate of Analysis

Certificate of Origin

A R Nicholas et al.
Biochimica et biophysica acta, 1463(1), 167-178 (2000-01-13)
Liposomes have been prepared by the vesicle extrusion method (VETs) from mixtures of dipalmitoylphosphatidylcholine (DPPC), phosphatidylinositol (PI) and dipalmitoylphosphatidylethanolamine with covalently linked poly(ethylene glycol) molecular mass 5000 and 2000 (DPPE-PEG 5000 and DPPE-PEG 2000) covering a range of 0-7.5 mole%....
Samantha A Meenach et al.
International journal of nanomedicine, 8, 275-293 (2013-01-29)
Novel advanced spray-dried and co-spray-dried inhalable lung surfactant-mimic phospholipid and poly(ethylene glycol) (PEG)ylated lipopolymers as microparticulate/nanoparticulate dry powders of biodegradable biocompatible lipopolymers were rationally formulated via an organic solution advanced spray-drying process in closed mode using various phospholipid formulations and...
Esra Ilhan-Ayisigi et al.
Macromolecular bioscience, 20(6), e2000084-e2000084 (2020-04-30)
In this study, the neoplastic drug frequently used in the treatment of lung cancer, carboplatin is loaded to microbubbles via a microfluidic platform. In order to increase the drug loading capacity of microbubbles, carboplatin is encapsulated into alginate polymer layer....
David Garenne et al.
Biomacromolecules, 21(7), 2808-2817 (2020-05-23)
Building genetically programmed synthetic cell systems by molecular integration is a powerful and effective approach to capture the synergies between biomolecules when they are put together. In this work, we characterized quantitatively the effects of molecular crowding on gene expression...
Mark J Richards et al.
Langmuir : the ACS journal of surfaces and colloids, 33(5), 1285-1294 (2017-01-18)
The supported lipid bilayer has been portrayed as a useful model of the cell membrane compatible with many biophysical tools and techniques that demonstrate its appeal in learning about the basic features of the plasma membrane. However, some of its...

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