18:1 PEG5000 PE

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (ammonium salt), chloroform

CAS Number:


pkg of 1 × 2.5 mL (880230C-25mg)
pkg of 2 × 4 mL (880230C-200mg)


Avanti Polar Lipids 880230C


10 mg/mL (880230C-25mg)
25 mg/mL (880230C-200mg)

shipped in

dry ice

storage temp.


SMILES string



18:1 PEG5000 PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in small unilamellar vesicles (SUV).

Biochem/physiol Actions

18:1 PEG5000 PE, also known as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000], is used along with lipid modified dendrimer copolymer to co-deliver siRNA and drugs to tumors.


5 mL Clear Glass Sealed Ampule (880230C-200mg)
5 mL Clear Glass Sealed Ampule (880230C-25mg)


Skull and crossbonesHealth hazard

Signal Word



Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system


6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK Germany


Flash Point(F)

does not flash

Flash Point(C)

does not flash

Certificate of Analysis

Certificate of Origin

Xiaolei Su et al.
Methods in molecular biology (Clifton, N.J.), 1584, 65-76 (2017-03-04)
Biochemical reconstitution has served as an important tool for understanding the mechanisms of many cellular processes including DNA replication, transcription, translation, vesicle trafficking, and ubiquitin-mediated proteolysis. Here, we demonstrate that biochemical reconstitution can be applied to studying a complex signaling...
TCR--pMHC bond conformation controls TCR ligand discrimination
Sasmal DK, et al.
Cellular & Molecular Immunology, 65-76 (2017)
Reconstitution of TCR signaling using supported lipid bilayers
Su X, et al.
Methods in Molecular Biology (2017)
Dibyendu K Sasmal et al.
Cellular & molecular immunology, 17(3), 203-217 (2019-09-19)
A major unanswered question is how a TCR discriminates between foreign and self-peptides presented on the APC surface. Here, we used in situ fluorescence resonance energy transfer (FRET) to measure the distances of single TCR-pMHC bonds and the conformations of...
Jiayi Pan et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 136, 18-28 (2019-01-12)
Multidrug resistance (MDR) significantly decreases the therapeutic efficiency of anti-cancer drugs. Its reversal could serve as a potential method to restore the chemotherapeutic efficiency. Downregulation of MDR-related proteins with a small interfering RNA (siRNA) is a promising way to reverse...

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