14:0 Diether PC (phosphocholine) is a glycerophospholipid having choline as the alcohol moiety, attached to the phosphate group. It has two tetradecyl chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds.
14:0 Diether PC or 1,2-di-O-tetradecyl-sn-glycero-3-phosphocholine might be used:
to prepare bicelle samples for solid-state NMR experiment
to compose isotropically tumbling small bicelles, to study its size and morphology
in lipid bicelles to reconstitute EmrE (secondary active transport protein)
Langmuir : the ACS journal of surfaces and colloids, 36(10), 2644-2653 (2020-02-20)
The lack of carbonyl groups and the presence of ether bonds give the lipid interphase a different water organization around the phosphate groups that affects the compressibility and electrical properties of lipid membranes. Generalized polarization of 1,2-di-O-tetradecyl-sn-glycero-3-phosphocholine (14:0 diether PC)...
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