LM6005

Avanti

Cer/Sph Mixture II

Ceramide/Sphingoid Internal Standard Mixture II, ethanol solution

NACRES:
NA.25

form

ethanol solution

packaging

pkg of 1 × 1 mL (LM6005-1EA)

manufacturer/tradename

Avanti Polar Lipids LM6005

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

shipped in

dry ice

storage temp.

−20°C

Application

Cer/Sph Mixture II has been used: as an internal standard mixture for sphingolipids quantification by liquid chromatography electrospray ionization-tandem mass spectrometry (LC ESI-MS/MS), in liquid chromatography-mass spectrometry (LC-MS) analysis for quality control check on the instrumental stability, internal standards mix for lipid extraction from serum and tissue samples by methyl-tert-butyl ether (MTBE)/methanol extraction method.

Packaging

2 mL Amber Glass Sealed Ampule (LM6005-1EA)

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Precautionary Statements

hazcat

Eye Irrit. 2 - Flam. Liq. 2

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Merja Joensuu et al.
Progress in neuro-psychopharmacology & biological psychiatry, 84(Pt B), 362-381 (2017-09-06)
Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the postsynaptic part of most excitatory synapses. Changes in the shape and size of dendritic spines correlate with the functional changes in excitatory synapses and are heavily dependent on...
Jeffrey Molendijk et al.
Biomolecules, 10(5) (2020-05-21)
Esophageal adenocarcinoma (EAC) incidence has been rapidly increasing, potentially associated with the prevalence of the risk factors gastroesophageal reflux disease (GERD), obesity, high-fat diet (HFD), and the precursor condition Barrett's esophagus (BE). EAC development occurs over several years, with stepwise...
Ken Cheng et al.
Journal of agricultural and food chemistry, 66(33), 8876-8884 (2018-07-26)
Membrane lipids, including sphingolipids and glycerol-phospholipids, are essential in maintaining the skin's barrier function in mammals, but their composition in fish skin and their response to diets have not been evaluated. This study investigated the impacts of reducing dietary eicosapentaenoic...
Seema Khurana et al.
FEBS letters, 582(14), 2128-2139 (2008-03-01)
Villin is a tissue-specific actin modifying protein that is associated with actin filaments in the microvilli and terminal web of epithelial cells. It belongs to a large family of actin-binding proteins which includes actin-capping, -nucleating and/or -severing proteins such as...
Nitai C Hait et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 4293-4310 (2020-02-06)
Sphingosine kinase 2 (SphK2) is known to phosphorylate the nuclear sphingolipid metabolite to generate sphingosine-1-phosphate (S1P). Nuclear S1P is involved in epigenetic regulation of gene expression; however, the underlying mechanisms are not well understood. In this work, we have identified...

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