A-144
Acylcarnitines Mix 2 (C4,iC4,C5,iC5,C6,C8,C10,C12,C14,C18) solution
100-200 μg/mL (90:10 Methanol: 1% aqueous formic acid), certified reference material, ampule of 1 mL, Cerilliant®
Synonym(s):
Acylcarnitines Mix 2 Solution
About This Item
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
composition
Butyryl-L-carnitine, 100 μg/mL
Decanoyl-L-carnitine, 100 μg/mL
Hexanoyl-L-carnitine, 100 μg/mL
Isobutyryl-L-carnitine, 100 μg/mL
Isovaleryl-L-carnitine, 100 μg/mL
Lauroyl-L-carnitine, 100 μg/mL
Myristoyl-L-carnitine, 100 μg/mL
Octanoyl-L-carnitine, 100 μg/mL
Stearoyl-L-carnitine, 200 μg/mL
Valeryl-L-carnitine, 100 μg/mL
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100-200 μg/mL (90:10 Methanol: 1% aqueous formic acid)
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
multi-component solution
storage temp.
−70°C
General description
Application
- Metabolic Disorder Biomarker Development: Acylcarnitines are crucial in diagnosing very long-chain acyl-CoA dehydrogenase deficiency. This research utilizes acylcarnitine profiles to improve understanding and treatment approaches for metabolic disorders, employing mass spectrometry metabolites for precise analysis (Bleeker JC et al., 2020).
- High-Purity Acylcarnitine Standards in Research: The study demonstrate the simultaneous extraction of metabolomes and lipidomes, including acylcarnitines, using ultra-high performance liquid chromatography/mass spectrometry. This methodology supports high-precision studies in fatty acid oxidation and metabolic assay development (Chen S et al., 2013).
- Application in Inborn Errors of Metabolism Assay: The research investigates how dietary bioactive polyphenols affect the mitochondrial carnitine acylcarnitine carrier, showcasing the utility of acylcarnitines in studying the impact of natural compounds on metabolic pathways, vital for understanding inborn errors of metabolism (Console L et al., 2019).
Legal Information
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Storage Class
3 - Flammable liquids
wgk_germany
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Certificates of Analysis (COA)
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Articles
In this article we provide a complete workflow of quantification and identification of acylcarnitines in dried blood spots (DBS) using stable isotope-labeled (SIL) acylcarnitines CRMs by FIA-MS/MS.
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