C-117

Corticosterone solution

Name: Corticosterone solution
Brand: CERILLIAN
Price: 106 USD

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₃₀O₄

CAS Number:

50-22-6

Molecular Weight:

346.46

NACRES:

NA.24

PubChem Substance ID:

329774873

UNSPSC Code:

41116107

MDL number:

MFCD00037715

Key Documents

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Product Name

Corticosterone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

InChI

1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1

SMILES string

CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO

InChI key

OMFXVFTZEKFJBZ-HJTSIMOOSA-N

grade

certified reference material

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Related Categories

Certified Reference Materials

Controlled Substances & Illicit Drug Standards

Biomarker & Metabolite Standards

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Show Differences

1 of 4

This Item	C-106	27840	P-104
Supelco C-117 Corticosterone solution	Supelco C-106 Cortisol solution	Sigma-Aldrich 27840 Corticosterone	Supelco P-104 Pregnenolone solution
application(s) clinical testing clinical testing	application(s) clinical testing clinical testing	application(s) -	application(s) clinical testing clinical testing
technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) -	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable
form liquid	form liquid	form powder or crystals	form liquid
format single component solution	format single component solution	format -	format single component solution
Quality Level 300	Quality Level 300	Quality Level 200	Quality Level 300
grade certified reference material	grade certified reference material	grade -	grade certified reference material

General description

Corticosterone is a corticosteroid and aldosterone precursor produced in the adrenal glands. Serum corticosterone levels are measured by LC-MS/MS for newborn screening and diagnosis of 11-hydroxylase deficiency.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

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Behavioral and corticotropic effects of ACTH during early postnatal ontogeny in rats.

T V Shemenkova et al.

Bulletin of experimental biology and medicine, 154(4), 464-466 (2013-03-15)

ACTH1-24(1 mg/kg) administered to 5-7-day-old rats reduced their locomotor activity and did not alter blood levels of corticosterone. ACTH administration on postnatal days 12-14 increased corticosterone levels, but had no effect on locomotor activity. Thus, the behavioral effect of ACTH

Effects of age on ACTH, corticosterone, glucose, insulin, and mRNA levels during intermittent hypoxia in the neonatal rat.

Kathan Chintamaneni et al.

American journal of physiology. Regulatory, integrative and comparative physiology, 304(9), R782-R789 (2013-03-15)

Apnea, the temporary cessation of respiratory airflow, is a common cause of intermittent hypoxia (IH) in premature infants. We hypothesized that IH elicits a stress response and alters glucose homeostasis in the neonatal rat. Rat pups were studied on postnatal

Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs.

Atish Mukherji et al.

Cell, 153(4), 812-827 (2013-05-15)

Alterations of symbiosis between microbiota and intestinal epithelial cells (IEC) are associated with intestinal and systemic pathologies. Interactions between bacterial products (MAMPs) and Toll-like receptors (TLRs) are known to be mandatory for IEC homeostasis, but how TLRs may time homeostatic

Electrical chronic vagus nerve stimulation activates the hypothalamic-pituitary-adrenal axis in rats fed high-fat diet.

Krzysztof Gil et al.

Neuro endocrinology letters, 34(4), 314-321 (2013-06-28)

The brain and the gut communicate bi-directionally through the brain-gut axis. The key role in such interactions plays autonomic nervous system and its major component, the vagus nerve. There is growing evidence that vagus nerve stimulation (VNS) has a suppressive

Perinatal broiler physiology between hatching and chick collection in 2 hatching systems.

L J F van de Ven et al.

Poultry science, 92(4), 1050-1061 (2013-03-09)

Little is known about physiological responses of early- versus late-hatching chicks to early posthatch conditions in broiler practice. We investigated effects of hatching time on perinatal broiler physiology in 2 hatching systems, differing in conditions: a conventional hatcher, where chicks

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