D-111
N-Desmethylzopiclone solution
100 μg/mL in acetonitrile, certified reference material, Cerilliant®
About This Item
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
100 μg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
SMILES string
ClC(C=N1)=CC=C1N(C2=O)C(OC(N3CCNCC3)=O)C4=C2N=CC=N4
InChI
1S/C16H15ClN6O3/c17-10-1-2-11(21-9-10)23-14(24)12-13(20-4-3-19-12)15(23)26-16(25)22-7-5-18-6-8-22/h1-4,9,15,18H,5-8H2
InChI key
CGSFZSTXVVJLIX-UHFFFAOYSA-N
Related Categories
General description
Application
<li><strong>Pharmacokinetic study of zopiclone metabolites:</strong> An in-depth examination of pharmacokinetics, focusing on zopiclone and its metabolites, including N-Desmethylzopiclone, to assess their distribution in hair samples post-administration it is used as an additional marker to confirm the intake of zopiclone (Hansen et al., 2020).</li>
<li><strong>Enantioselective analysis after biotransformation:</strong> The study developed a new and rapid method for the enantioselective analysis of N-Desmethylzopiclone, using fungal biotransformation, crucial for understanding metabolic pathways and anxiolytic activity in pharmaceutical research(de Albuquerque et al., 2015).</li>
<li><strong>Validation of analytical methods for forensic application:</strong> A validated LC-MS/MS method for determining zopiclone, N-Desmethylzopiclone, and other related compounds in blood, providing a reliable tool for forensic and clinical toxicology analyses (Nilsson et al., 2015).</li>
<li><strong>Quantitative analysis in urine:</strong> A comprehensive study on the quantitative analysis of zopiclone and its derivatives, including N-Desmethylzopiclone, in urine using LC-MS-MS, supporting drug monitoring and toxicological investigations (Nilsson et al., 2014).</li>
</ul>
Legal Information
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
wgk_germany
WGK 2
flash_point_f
closed cup
flash_point_c
closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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