H-059

6β-Hydroxytestosterone solution

Name: 6β-Hydroxytestosterone solution
Brand: CERILLIAN
Price: 118 USD

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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About This Item

Empirical Formula (Hill Notation):

C₁₉H₂₈O₃

CAS Number:

62-99-7

Molecular Weight:

304.42

NACRES:

NA.24

PubChem Substance ID:

329815121

UNSPSC Code:

41116107

EC Number:

200-659-6

MDL number:

MFCD00171612

Key Documents

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Product Name

6β-Hydroxytestosterone solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

InChI key

XSEGWEUVSZRCBC-ZVBLRVHNSA-N

InChI

1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1

SMILES string

C[C@]12CC[C@H]3[C@@H](C[C@@H](O)C4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O

grade

certified reference material

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Related Categories

Analytical Chemistry

Certified Reference Materials

Controlled Substances & Illicit Drug Standards

Reference Materials

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Show Differences

1 of 4

This Item	T-034	A-075	M-080
Supelco H-059 6β-Hydroxytestosterone solution	Supelco T-034 6β-Hydroxytestosterone-D₃ solution	Supelco A-075 Androstenedione solution	Supelco M-080 Methylmalonic acid solution
technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable
format single component solution	format single component solution	format single component solution	format single component solution
form liquid	form liquid	form liquid	form liquid
Quality Level 300	Quality Level 300	Quality Level 300	Quality Level 300
grade certified reference material	grade certified reference material	grade certified reference material	grade certified reference material
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

General description

A Certified Spiking Solution^® suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from clinical and diagnostic testing to endocrinology and sports testing. 6ß-Hydroxytestosterone is a major urinary metabolite of testosterone, a hormone from the androgen group of steroids. Testosterone is an important sex hormone and anabolic steroid used as a performance-enhancing drug.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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T-034

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pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Syntheses of stable isotope-labeled 6 beta-hydroxycortisol, 6 beta-hydroxycortisone, and 6 beta-hydroxytestosterone.

Takashi Furuta et al.

Steroids, 68(7-8), 693-703 (2003-09-06)

A method is described for the preparation of two types of multi-labeled 6 beta-hydroxycortisol containing either five deuterium atoms at C-19 methyl and C-1 methylene or four 13C atoms at C-1, C-2, C-4, and C-19 in addition to the five

Comparison of the inhibitory profiles of itraconazole and cimetidine in cytochrome P450 3A4 genetic variants.

Takeshi Akiyoshi et al.

Drug metabolism and disposition: the biological fate of chemicals, 39(4), 724-728 (2011-01-08)

CYP3A4, an important drug-metabolizing enzyme, is known to have genetic variants. We have previously reported that CYP3A4 variants such as CYP3A4.2, 7, 16, and 18 show different enzymatic kinetics from CYP3A4.1 (wild type). In this study, we quantitatively investigated the

Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.

Furong Qiu et al.

Xenobiotica; the fate of foreign compounds in biological systems, 40(12), 800-806 (2010-10-23)

This study evaluated the in vitro activation of CYP3A-mediated midazolam 1-hydroxylation and testosterone 6β-hydroxylation by tanshinone I, tanshinone IIA, and cryptotanshinone. The abilities of tanshinones to activate CYP3A-mediated midazolam 1-hydroxylation and testosterone 6β-hydroxylation in human liver microsomes (HLMs) were tested.

An assessment of udp-glucuronosyltransferase induction using primary human hepatocytes.

Matthew G Soars et al.

Drug metabolism and disposition: the biological fate of chemicals, 32(1), 140-148 (2004-01-08)

Uridine diphosphate glucuronosyltransferases (UGTs) catalyze the glucuronidation of a wide range of xenobiotics and endogenous substrates. However, there is a lack of information concerning the response of human UGTs to inducers, and this observation prompted the current investigation. The glucuronidation

High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry.

Jin Wu et al.

Analytical chemistry, 79(12), 4657-4665 (2007-05-15)

This paper describes the development of a high-throughput method for the analysis of cytochrome P450 (CYP) inhibition assay incubation samples using laser diode thermal desorption interfaced with atmospheric pressure chemical ionization mass spectrometry (LDTD-APCI-MS). Data for the CYP isoforms 3A4

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