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I-033

Supelco

IGF-1 solution

100 μg/mL (2% Acetic acid, 2mM Methionine, pH as is), certified reference material, pkg of 1 mL (Cryoules), Cerilliant®

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CAS Number:

grade

certified reference material

Quality Level

form

liquid

mol wt

7654.74 Da

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

pkg of 1 mL (Cryoules)

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL (2% Acetic acid, 2mM Methionine, pH as is)

technique(s)

liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

shipped in

dry ice

storage temp.

−20°C

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I-033

IGF-1 solution

Sigma-Aldrich

Sigma-Aldrich

SRP3069

IGF-I human

Testosterone solution 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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T-037

Testosterone solution

Corticosterone solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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C-117

Corticosterone solution

format

single component solution

format

-

format

single component solution

format

single component solution

form

liquid

form

lyophilized powder

form

liquid

form

liquid

mol wt

7654.74 Da

mol wt

~7.6 kDa

mol wt

-

mol wt

-

feature

Snap-N-Spike®/Snap-N-Shoot®

feature

-

feature

Snap-N-Spike®/Snap-N-Shoot®

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

pkg of 1 mL (Cryoules)

packaging

pkg of 100 μg, pkg of 50 μg

packaging

ampule of 1 mL

packaging

ampule of 1 mL

General description

Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a protein hormone that plays an important role in childhood growth and continues to have anabolic effects in adults. Measuring IGF-1 levels is used to test for growth hormone deficiency and excess in acromegaly and gigantism. This certified Snap-N-Spike® solution of the fully-intact IGF-1 protein is suitable for use as starting material for calibrators and controls in IGF-1 LC/MS testing applications.
The quantitative analysis of IGF-I has played a crucial role in diagnosing and treating human growth disorders ever since its serum measurement became widely accessible. IGF-1 serves as a biomarker for growth hormone (GH) activity. This product is a certified reference material containing a human insulin solution. The insulin contained in this product is derived from recombinant sources of human origin. It is prepared in line with the ISO guidelines and satisfies the criteria for both certified reference material and primary standard categories. It is traceable to higher-order standards through an unbroken chain of comparisons. Furthermore, it is created from a pure substance in an aqueous solvent solution, which constitutes a primary standard.

Application

IGF-1 solution is suitable for the in vitro identification, calibration, and quantification of the analyte(s) in analytical and R&D applications.

Features and Benefits

  • The content of IGF-1 is determined using quantitative amino acid analysis (AAA) and HPLC/UV/MS.
  • No adjustments required before using this standard.
  • It has been prepared and certified in accordance with the ISO 17034, ISO/IEC 17025, and ISO 9001 standards.
  • All raw materials used in the product have undergone comprehensive identification and characterization processes utilizing various analytical techniques.
  • Long-term stability has been evaluated for storage in freezer conditions (-10 °C to -25 °C).

Preparation Note

  • Prior to use, thaw the product either in the refrigerator or at room temperature, and ensure thorough mixing.
  • Do not attempt to refreeze the product once thawed.
  • Thawed product can be stored in a refrigerated environment for up to 8 weeks.
  • When using the product, it is recommended that users quantitatively transfer the desired volume, following established good laboratory practices. This can be done either to spike it into a matrix or to dilute it to the desired concentration.

Other Notes

This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. Refer to the safety data sheet for specific details regarding any possible hazards and necessary precautions.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Narrow mass extraction of time-of-flight data for quantitative analysis of proteins: determination of insulin-like growth factor-1
Bystrom CE, et al.
Analytical Chemistry, 83(23) (2011)
Discordance between mass spectrometry and immunometric IGF-1 assay in pituitary disease: a prospective study
Bonert V, et al.
Pituitary, 21(1) (2018)
Clinical utility of insulin-like growth factor 1 and 2; determination by high resolution mass spectrometry
Bystrom C, et al.
Testing, 7(9) (2012)
Clinical utility of insulin-like growth factor 1 and 2; determination by high resolution mass spectrometry
Bystrom C, et al.
PLoS ONE, 7(9) (2012)

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