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MilliporeSigma

I-902

Imipramine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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1 ML

$29.50

$29.50


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About This Item

Empirical Formula (Hill Notation):
C19H24N2 · HCl
CAS Number:
Molecular Weight:
316.87
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6

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InChI key

XZZXIYZZBJDEEP-UHFFFAOYSA-N

InChI

1S/C19H24N2.ClH/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21;/h3-6,8-11H,7,12-15H2,1-2H3;1H

SMILES string

Cl.CN(C)CCCN1c2ccccc2CCc3ccccc13

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

Quality Level

Gene Information

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This Item
PHR1797I01000001338007
application(s)

clinical testing

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

form

liquid

form

-

form

-

form

-

Quality Level

300

Quality Level

300

Quality Level

-

Quality Level

-

grade

certified reference material

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

-

storage temp.

-

General description

Imipramine, also known as melipramine, is a tricyclic antidepressant prescribed for the treatment of major depression, enuresis, and anxiety disorder. This certified solution standard is suitable for use in forensic analysis, clinical toxicology, or urine drug testing applications by LC-MS/MS or GC/MS. Imipramine is marketed under the trade name Tofranil.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Certificates of Analysis (COA)

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Pablo Méndez et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(47), 16616-16628 (2012-11-24)
Correct brain functioning relies on the precise activity of a myriad of synapses assembling neurons in complex networks. In the hippocampus, highly diverse inhibitory circuits differently govern several physiologically relevant network activities. Particularly, perisomatic inhibition provided by specific interneurons was
Adam J Walker et al.
Behavioural brain research, 242, 76-83 (2013-01-02)
Several animal models are currently utilised in the investigation of major depressive disorder; however, each is validated by its response to antidepressant pharmacotherapy. Few animal models consider the notion of antidepressant treatment resistance. Chronic daily administration of adrenocorticotropic hormone (ACTH)
Gislaine Z Réus et al.
Behavioural brain research, 242, 40-46 (2012-12-15)
A growing body of evidence is pointing toward an association between immune molecules, as well brain-derived neurotrophic factor (BDNF) and the depression. The present study was aimed to evaluate the behavioral and molecular effects of the antidepressant imipramine in maternally
Tatyana Strekalova et al.
Behavioural brain research, 245, 101-106 (2013-02-26)
Tricyclics and selective serotonin reuptake inhibitors (SSRIs) are probably the most widely employed reference antidepressants in animal studies on depression. Using imipramine and citalopram, we sought to assess which drug would be more appropriate as pharmacological reference in paradigms of
D J Hines et al.
Translational psychiatry, 3, e212-e212 (2013-01-17)
Major depressive disorder is a debilitating condition with a lifetime risk of ten percent. Most treatments take several weeks to achieve clinical efficacy, limiting the ability to bring instant relief needed in psychiatric emergencies. One intervention that rapidly alleviates depressive

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