M-007

Supelco

(±)-Methadone solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Empirical Formula (Hill Notation):
C21H27NO
CAS Number:
Molecular Weight:
309.45
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

grade

certified reference material

packaging

ampule of 1 mL

mfr. no.

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1 mg/mL in methanol

Featured Industry

Pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)=O

InChI

1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3

InChI key

USSIQXCVUWKGNF-UHFFFAOYSA-N

Gene Information

human ... OPRM1(4988)

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General description

Methadone is a synthetic opioid used medically as an analgesic and as a maintenance anti-addictive for use in patients with opioid dependency. The drug is sold under several trade names such as Symoron, Dolophine®, Amidone, Methadose®, Physeptone, or Heptadon. This Certified Spiking Solution® is suitable for LC/MS or GC/MS testing methods in pain prescription monitoring, forensic analysis or clinical toxicology.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Dolophine is a registered trademark of Roxane Laboratories, Inc.
Methadose is a registered trademark of Mallinckrodt Inc.

Signal Word

Danger

Target Organs

Eyes

RIDADR

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificate of Analysis
Certificate of Origin
Maintenance medication for opiate addiction: the foundation of recovery.
Bart G.
Journal of Addictive Diseases, 31(3), 207-225 (2012)
David Kao et al.
Annals of internal medicine, 158(10), 735-740 (2013-05-22)
Long-acting opioids are a leading cause of accidental death in the United States, and methadone is associated with greater mortality rates. Whether this increase is related to the proarrhythmic properties of methadone is unclear. To describe methadone-associated arrhythmia events reported...
Advice on methadone and oral health: dental public health in action.
C M Jones et al.
Community dental health, 30(2), 68-70 (2013-07-31)
The lethal burden of drug overdose.
Lancet (London, England), 382(9895), 833-833 (2013-09-10)
Philippa Hawley et al.
Pain research & management, 18(2), 83-86 (2013-05-11)
Methadone is one of the most important medications used for the treatment of refractory pain in the palliative care setting, and is usually initially prescribed by one of a limited number of physicians who have acquired authorization for its use....
Articles
Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.
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