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M-123

Supelco

Metoprolol tartrate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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Empirical Formula (Hill Notation):
C15H25NO3 · 0.5 C4H6O6
CAS Number:
Molecular Weight:
342.41
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

CC(C)NCC(COC1=CC=C(CCOC)C=C1)O.CC(C)NCC(COC2=CC=C(CCOC)C=C2)O.OC(C(O)=O)C(C(O)=O)O

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)

InChI key

YGULWPYYGQCFMP-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153)

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This Item
PHR1076B-037N-907
vibrant-m

M-123

Metoprolol tartrate solution

vibrant-m

PHR1076

Metoprolol Tartrate

vibrant-m

B-037

Butorphanol tartrate solution

application(s)

clinical testing

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

forensics and toxicology

application(s)

clinical testing

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

form

liquid

form

-

form

liquid

form

liquid

grade

certified reference material

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material

grade

certified reference material

General description

A certified solution standard applicable for use in clinical toxicology or forensic analysis by LC-MS/MS or GC/MS. Metoprolol is used for the treatment of multiple heart conditions including hypertension, angina, and tachycardia. This beta blocker is sold under the trade names Lepressor and Toprol XL®.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Toprol XL is a registered trademark of Astrazeneca AB

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


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Metoprolol Tartrate Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1076

Metoprolol Tartrate

Atenolol ≥98% (TLC), powder

Sigma-Aldrich

A7655

Atenolol

Thomas Kahan et al.
European journal of clinical investigation, 43(2), 141-151 (2013-01-03)
Although stable angina pectoris often carries a favourable prognosis, it remains important to identify patients with an increased risk of cardiovascular (CV) complications. Many new markers of disease activity and prognosis have been described. We evaluated whether common and easily
A L Vertkin et al.
Klinicheskaia meditsina, 91(3), 31-35 (2013-06-26)
Patients with acute coronary syndrome and elevated ST segment in the pre-hospital phase were treated with metoprolol succinate (MS) and thrombolytic therapy. Severe and moderate pain decreased by 54.1 and 16.1% respectively within 60 min after MS intake. Systolic (SAP)
Iu M Alekseeva et al.
Kardiologiia, 52(11), 86-91 (2012-12-15)
We present analysis of a case history of a patient with rare congenital heart disorder - Bland-White-Garland syndrome. The 25 years old women was first diagnosed with this disorder during an examination in the cardiological department of the Moscow clinical
Angela Price et al.
Hypertension (Dallas, Tex. : 1979), 61(6), 1263-1269 (2013-04-03)
In young healthy humans, sympathetic vasoconstriction is markedly blunted during exercise to optimize blood flow to the metabolically active muscle. This phenomenon known as functional sympatholysis is impaired in hypertensive humans and rats by angiotensin II-dependent mechanisms, involving oxidative stress
Abdulhakim A A Khaled et al.
Acta poloniae pharmaceutica, 70(4), 743-747 (2013-08-08)
This study was aimed to develop level A, B and C in vitro-in vivo correlation (IVIVC) for encapsulated metoprolol tartrate (T1, T2 and T3 having metoprolol tartrate/polymer ratio of 1: 1, 1: 1.5 and 1: 2,w/w). The in vitro data

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