O-004

Supelco

Oxymorphone solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Empirical Formula (Hill Notation):
C17H19NO4
CAS Number:
Molecular Weight:
301.34
MDL number:
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

Quality Level

grade

certified reference material

CofA

certificate is enclosed in each package

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

mfr. no.

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in methanol

application(s)

HPLC: suitable
gas chromatography (GC): suitable

Featured Industry

Pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

SMILES string

CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35

InChI

1S/C17H19NO4/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9/h2-3,12,15,19,21H,4-8H2,1H3/t12-,15+,16+,17-/m1/s1

InChI key

UQCNKQCJZOAFTQ-ISWURRPUSA-N

Gene Information

human ... OPRD1(4985), OPRK1(4986), OPRM1(4988)

General description

A certified Snap-N-Spike® solution of oxymorphone suitable for use in a variety of GC/MS or LC/MS applications from pain prescription monitoring, clinical toxicology, and pharmaceutical research to forensic analysis and urine drug testing. Oxymorphone, sold under trade names such as Opana®, Numorphan®, and Numorphone, is an opiate analgesic indicated for the relief of moderate to severe pain.

Legal Information

CERILLIANT is a registered trademark of Cerilliant Corporation
Numorphan is a registered trademark of Endo Pharmaceuticals Inc.
Opana is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

Signal Word

Danger

Target Organs

Eyes

Hazard Codes

F,T

Risk Statement

11-23/24/25-39/23/24/25

Safety Statement

16-36/37-45

RIDADR

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificate of Analysis
Certificate of Origin
M Spetea et al.
Current medicinal chemistry, 19(15), 2442-2457 (2012-03-30)
Morphine and other opioid morphinans produce analgesia primarily through μ opioid receptors (MORs), which mediate beneficial but also non-beneficial actions. There is a continued search for efficacious opioid analgesics with reduced complications. The cornerstone in the development of 14-alkoxymorphinans as...
Deborah French et al.
Bioanalysis, 3(23), 2603-2612 (2011-12-06)
In clinical laboratories, a large proportion of the toxicology workload is drug confirmations. Our GC-MS method for opioid confirmation detects total codeine, morphine, hydrocodone, hydromorphone, oxycodone and oxymorphone. The objective of this study was to develop a LC-MS/MS assay measuring...
Marco Pappagallo et al.
Postgraduate medicine, 124(5), 101-109 (2012-10-26)
Because rates of both opioid prescribing and opioid abuse have increased, drug companies have responded by considering strategies to make opioid formulations less attractive for abuse without compromising safety or efficacy for patients with legitimate pain management needs. The emergence...
Trine Naalsund Andreassen et al.
European journal of clinical pharmacology, 68(1), 55-64 (2011-07-08)
Opioids are recommended by the World Health Organization for moderate to severe cancer pain. Oxycodone is one of the most commonly used opioids and is metabolized in the liver by CYP3A4 and CYP2D6 enzymes. The aim of this cross-sectional study...
Mark P Jensen et al.
The Clinical journal of pain, 29(4), 289-295 (2012-10-09)
To understand the factors that contribute to patient and physician global outcome ratings and the extent to which receiving different doses of opioids or placebo might influence the importance of these factors better. A secondary analysis was performed using data...
Articles
Although both biphenyl and phenyl-hexyl phases can resolve these compounds, the former exhibits excellent peak shape and substantially less silanol-derived ion exchange activity.
Read More
Protocols
To optimize hydrolysis using β-glucuronidase, factors such as incubation time, temperature, hydrolysis pH, enzyme source, and enzyme concentration must be evaluated for each glucuronide metabolite to be analyzed.
Read More

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