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P-917

Supelco

Acetaminophen-D4 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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Empirical Formula (Hill Notation):
C8D4H5NO2
CAS Number:
Molecular Weight:
155.19
EC Number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

2-8°C

SMILES string

[2H]c1c([2H])c(NC(C)=O)c([2H])c([2H])c1O

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)/i2D,3D,4D,5D

InChI key

RZVAJINKPMORJF-QFFDRWTDSA-N

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General description

A stable-labeled internal standard suitable for quantitation of acetaminophen levels in urine, serum, or plasma by LC/MS or GC/MS for clinical toxicology, isotope dilution methods, P450 studies, and other pharmaceutical research. Acetaminophen, or Paracetamol, is a common over-the-counter COX inhibitor drug used for pain relief and fever reduction.

Application

  • Simultaneous determination of acetaminophen and oxycoDonein human plasma by LC-MS/MS and its application to a pharmacokinetic study: This research demonstrates the application of Acetaminophen-D4 as an internal standard in the simultaneous analysis of acetaminophen and oxycoDoneusing LC-MS/MS. The study provides critical insights into drug metabolism and pharmacokinetic profiling, offering a reliable method for therapeutic monitoring and drug interaction studies in clinical pharmacology (Lu et al., 2018).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

wgk_germany

WGK 1

flash_point_f

closed cup

flash_point_c

closed cup


Certificates of Analysis (COA)

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