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Millipore

SMC® Human Cardiac Troponin I (cTnI) Immunoassay Kit

Synonym(s):
cTnI Single Molecule Counting Kit, Cardiac Muscle Troponin I immunoassay kit, cTnI ultra-sensitive immunoassay, Cardiac Troponin I immunoassay kit
eCl@ss:
32161000

Quality Level

species reactivity

human, rat, guinea pig, canine, monkey

manufacturer/tradename

SMC®

assay range

accuracy: 80-120%
(minimum of 10 samples spiked with acceptable recovery)

technique(s)

ELISA: suitable
single molecule counting: suitable

General description

Cardiac Troponin-I (cTnI) is specific to cardiomyocytes and is released into the bloodstream following heart damage. Extensive studies have shown that cTnI is slowly released from damaged cardiomyocytes. This has allowed cTnI to become widely accepted in preclinical and clinical drug development settings as an indicator of myocardial damage and hence, heart damage.The high sensitivity of the research grade Erenna cTnI assay uniquely provides utility across multiple species and matrices.
The SMC® Human cTnI Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC® immunoassay system detects analytes using Single Molecule Counting (SMC®) technology.

Application

Research Sub Category
Cardiovascular Disease
Research Category
Cardiovascular Disease
The sensitivity of the Single Molecule Counting (SMC®) technology gives the SMC® Cardiac Troponin (cTnI) Immunoassay Kit unparalleled performance in the quantification of cTnI in human EDTA plasma and serum.
Used to detect/quantify:Cardiac Troponin I

Components

cTnI Coated Beads
Standard Diluent
cTnI Detection Antibody
Assay Buffer
cTnI Standard
10X Wash Buffer
Elution Buffer B
Buffer D
SMC® Human cTnI Immunoassay Kit Instructions

Analysis Note

Low-end CV% Range: 0-20%|Low-end CV% Average: 12%

Legal Information

SMC is a registered trademark of Singulex

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

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Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Certificate of Analysis

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Certificate of Quality

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