03-0219-00

SMC^® Human IL-22 Binding Protein High Sensitivity Immunoassay Kit

SMC^® advanced ultrasensitive immunoassay technology

• Synonym(s): IL-22 inhibitory protein immunoassay, IL-22 receptor antagnoist assay, high sensitivity IL-22BP assay, interleukin-22 binding protein high sensitivity assay, ultra-sensitive IL-22BP

Properties

• Quality Level: 200
• usage: kit sufficient for 96 wells
• quality: 200
• species reactivity: human
• manufacturer/tradename: SMC^®
• assay range: linearity: 113%; (Serum); linearity: 115%; (Plasma); recovery range: 116%; (Serum); recovery range: 98%; (Plasma); sensitivity: 1.95-7.81 pg/mL; (Refer to CoA for lot-specific LLOQ); standard curve range: 0.98-1,000 pg/mL
• technique(s): single molecule counting: suitable
• input: plasma (K2EDTA); serum
• shipped in: wet ice
• storage temp.: 2-8°C

Description

General description

IL-22 binding protein (IL-22BP) is a soluble protein that regulates the immune response by binding to IL-22 and preventing it from interacting with its receptor on target cells. This action serves as a negative regulator, helping maintain a balanced immune response and preventing excessive inflammation. IL-22BP may have therapeutic potential in treating autoimmune and inflammatory diseases by modulating IL-22 signaling.

Application

For ultrasensitive detection of IL-22BP in human serum and plasma

Features and Benefits

Features

• Robustness and Reproducibility: Lot-matched components ensure consistent assay performance across experiments, reducing variability and enhancing data reliability.
• Enhanced Detection Limits: Capable of detecting ultra-low analyte levels in the picogram and femtogram range, enabling the study of low-abundance biomarkers critical in early-stage research.
• Simplified Workflow Compatibility: Designed to align with standard assay workflows, including ELISA, minimizing the need for additional training or protocol adjustments.
• Certified Data Assurance: Each kit includes a Certificate of Analysis detailing validated assay characteristics, ensuring traceability and quality control for regulatory compliance.
• Wide Dynamic Range: Accurately quantifies analyte concentrations across a broad range, supporting both high and low abundance detection in complex samples.
• Automation Ready: Compatible with high-throughput systems, enabling seamless integration into automated workflows, reducing manual handling errors, and increasing efficiency.

Benefits

• Understanding Mechanisms: By accurately measuring IL-22BP levels, you can explore its role in immune responses and pathophysiology, enhancing your understanding of disease mechanisms.
• Monitoring Disease Models: This ultrasensitive assay facilitates tracking of IL-22BP levels over time in your samples, helping you gain insights for research into disease progression and treatment effects.
• Early Detection: With enhanced sensitivity, this assay allows you to detect low concentrations of IL-22BP, enabling early identification of inflammatory and autoimmune conditions in your studies.
• Integrated Analysis: Having both IL-22BP and IL-22 assays on the same platform allows for streamlined data collection and analysis, enabling you to correlate IL-22 levels with its binding protein in a single workflow.

Legal Information

SMC is a registered trademark of Singulex