05-168

Anti-TNFα Antibody, clone MPG-XT3

Name: Anti-TNFα Antibody, clone MPG-XT3
Brand: MM
Price: 405 USD

clone MPG-XT3, Upstate^®, from rat

Slide 1 of 1

Select a Size

1 MG

$405.00

Check Cart for Availability

Request a Bulk Order

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Key Documents

View All Documentation

Product Name

Anti-TNFα Antibody, clone MPG-XT3, clone MPG-XT3, Upstate^®, from rat

isotype

IgG1

biological source

rat

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MPG-XT3, monoclonal

species reactivity

mouse

manufacturer/tradename

Upstate^®

technique(s)

neutralization: suitable

NCBI accession no.

NM_000594.2

UniProt accession no.

P01375

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... TNF(7124)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	SAB4700870	SAB4701119	T0813
Sigma-Aldrich 05-168 Anti-TNFα Antibody, clone MPG-XT3	Sigma-Aldrich SAB4700870 Monoclonal Anti-TNFalpha antibody produced in mouse	Sigma-Aldrich SAB4701119 Monoclonal Anti-TNFalpha-APC antibody produced in mouse	Sigma-Aldrich T0813 Anti-Tumor Necrosis Factor-α antibody produced in goat
antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form affinity isolated antibody
species reactivity mouse	species reactivity nonhuman primates, pig, human	species reactivity -	species reactivity human
clone MPG-XT3, monoclonal	clone MAb11, monoclonal	clone MAb11, monoclonal	clone polyclonal
biological source rat	biological source mouse	biological source mouse	biological source goat
shipped in dry ice	shipped in wet ice	shipped in wet ice	shipped in -
Gene Information human ... TNF(7124)	Gene Information human ... TNF(7124)	Gene Information human ... TNF(7124)	Gene Information human ... TNF(7124)

Analysis Note

routinely used to neutralize 50% of the cytotoxic effect of recombinant mouse TNF-α on actinomycin D treated L929 cells.

Application

Research Category
Signaling

Research Sub Category
Growth Factors & Receptors

This Anti-TNFalpha Antibody, clone MPG-XT3 is validated for use in NEUT for the detection of TNFα.

Biochem/physiol Actions

mouse TNF-α; does not recognize human or rat TNF-α

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

17 kDa

The concentration of antibody needed to neutralize the bioactivity of TNF-α will depend on the cell type, the incubation conditions, and the biological response studied.

Immunogen

Recombinant murine TNF-α

Other Notes

Replaces: 04-1114

Physical form

0.01M Tris-glycine, 0.15M NaCl, pH 7.4

DEAE chromatography

Format: Purified

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii.

Hunter, C A, et al.

Infection and Immunity, 61, 4038-4044 (1993)

TNF-alpha is the critical mediator of the cyclic AMP-induced apoptosis of CD8+4+ double-positive thymocytes.

J A Guevara Patiño et al.

Journal of immunology (Baltimore, Md. : 1950), 164(4), 1689-1694 (2000-02-05)

Apoptosis is one of the key regulatory mechanisms in tissue modeling and development. In the thymus, 95-98% of all thymocytes die by apoptosis because they failed to express a TCR with an optimal affinity for the selecting intrathymic peptide-MHC complexes.

Dermatophagoides-farinae-induced pulmonary eosinophilic inflammation in mice.

C K Yu et al.

International archives of allergy and immunology, 112(1), 73-82 (1997-01-01)

Dermatophagoides farinae (Der f) is one of the most common species of dust mites that induce asthma and allergic rhinitis. We have reported that Der f challenge on sensitized mice elicited a distinct type of hypersensitivity, called early-type hypersensitivity (ETH)

A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade

Kobayashi, H., et al

The Journal of Biological Chemistry, 278, 7790-7799 (2003)

Role of laminin-1, collagen IV, and an autocrine factor(s) in regulated secretion by lacrimal acinar cells.

L Chen, J D Glass, S C Walton, G W Laurie

The American Journal of Physiology null

View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service