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Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1

Name: Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1
Brand: MM
Price: 476 USD

clone 22B1, Upstate^®, from mouse

Synonym(s):

Anti-Anti-CAMKA, Anti-Anti-CaMKIINalpha, Anti-Anti-CaMKIIalpha, Anti-Anti-MRD53, Anti-Anti-MRT63

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Pack Size	SKU	Availability	Price
100 μg		Check Cart for Availability	$476.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Clone:

22B1, monoclonal

Species reactivity:

rat

Application:

Citations:

$476.00

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Properties

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

22B1, monoclonal

species reactivity

rat

manufacturer/tradename

Upstate^®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NM_015981 (and others)

UniProt accession no.

Q9UQM7

shipped in

wet ice

target post-translational modification

phosphorylation (pThr286)

Gene Information

human ... CAMK2A(815)

Description

General description

50kDa

Immunogen

Peptide corresponding to residuues 281-294 of rat Cam Kinase II alpha-subunit; recognizes phosphorylated CaM Kinase II on Threonine 286

Application

Detect phospho-CaM Kinase II using this Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1 validated for use in WB.

Biochem/physiol Actions

phospho-CaM Kinase II α subunit

Physical form

Format: Purified

Analysis Note

routinely evaluated by immunoblot on rat brain microsomal protein preparation

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	05-532	07-1496	04-1479
Sigma-Aldrich 05-533 Anti-phospho-CaM Kinase II Antibody, α subunit, (Thr286), clone 22B1	Sigma-Aldrich 05-532 Anti-CaM Kinase II Antibody, α subunit, clone 6G9	Sigma-Aldrich 07-1496 Anti-CaM Kinase II Antibody	Sigma-Aldrich 04-1479 Anti-methyl-PP2A Antibody, C subunit, clone 2A10
species reactivity rat	species reactivity rat, bovine	species reactivity mouse, chicken, bovine, hamster, human, rabbit, rat, guinea pig	species reactivity yeast, human, Saccharomyces cerevisiae, mouse
antibody form purified antibody	antibody form purified immunoglobulin	antibody form affinity purified immunoglobulin	antibody form purified antibody
clone 22B1, monoclonal	clone 6G9, monoclonal	clone polyclonal	clone 2A10, monoclonal
biological source mouse	biological source mouse	biological source rabbit	biological source mouse
Gene Information human ... CAMK2A(815)	Gene Information human ... CAMK2A(815)	Gene Information human ... CAMK2A(815)	Gene Information human ... PPP2CA(5515)
technique(s) western blot: suitable	technique(s) immunohistochemistry: suitable, western blot: suitable	technique(s) western blot: suitable	technique(s) western blot: suitable

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Storage Class

10 - Combustible liquids

wgk

WGK 1

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Overexpression of calbindin-D28K in hippocampal progenitor cells increases neuronal differentiation and neurite outgrowth.

Kim, JH; Lee, JA; Song, YM; Park, CH; Hwang, SJ; Kim, YS; Kaang, BK; Son, H

Faseb Journal null

Autophosphorylation of type II CaM kinase in hippocampal neurons: localization of phospho- and dephosphokinase with complementary phosphorylation site-specific antibodies.

B L Patton et al.

Molecular biology of the cell, 4(2), 159-172 (1993-02-01)

We have visualized the distribution of autophosphorylated type II CaM kinase in neural tissue with the use of two complementary antibodies: a monoclonal antibody that binds to the alpha and beta subunits of the kinase only when they are autophosphorylated

Phosphorylation of CaMKII in the rat dorsal raphe nucleus plays an important role in sleep-wake regulation.

Su-Ying Cui et al.

Journal of neurochemistry, 136(3), 609-619 (2015-11-13)

The Ca(2+) modulation in the dorsal raphe nucleus (DRN) plays an important role in sleep-wake regulation. Calmodulin-dependent kinase II (CaMKII) is an important signal-transducing molecule that is activated by Ca(2+) . This study investigated the effects of intracellular Ca(2+) /CaMKII

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Global Trade Item Number

SKU	GTIN
05-533	04053252269264

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