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06-903

Sigma-Aldrich

Anti-PKA Antibody, NT

Upstate®, from rabbit

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eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

hamster, bovine, rat, pig, mouse, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TYRO3(7301)

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This Item
ABC12AB1650207-1232
Anti-PKA Antibody, NT Upstate®, from rabbit

Sigma-Aldrich

06-903

Anti-PKA Antibody, NT

Anti-Bak (NT) Antibody from rabbit, purified by affinity chromatography

Sigma-Aldrich

ABC12

Anti-Bak (NT) Antibody

antibody form

purified antibody

antibody form

affinity isolated antibody

antibody form

purified antibody

antibody form

serum

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

species reactivity

hamster, bovine, rat, pig, mouse, human

species reactivity

mouse, rat, human

species reactivity

human

species reactivity

human, mouse

manufacturer/tradename

Upstate®

manufacturer/tradename

-

manufacturer/tradename

Chemicon®

manufacturer/tradename

-

technique(s)

western blot: suitable

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

western blot: suitable

technique(s)

ELISA: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable

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Specificity

PKA, and recombinant human alpha isoform of PKA

Immunogen

peptide (KKGSEQESVKEFLAK-C) based upon amino acids 8-22 of the human 41kDa alpha isoform of the catalytic subunit of PKA

Application

Anti-PKA Antibody, NT detects level of PKA & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Quality

routinely evaluated by immunoblot on rat brain microsomal preparation or PC-12 RIPA cell lysates

Target description

41kDa

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol added to 30%
Format: Purified
Protein A chromatography

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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Ho-Lin Chuang et al.
Environmental toxicology, 36(9), 1873-1879 (2021-06-06)
Epimedium, is used traditionally in Chinese medicine to treat infertility problems. In this study, we establish the cell model to elucidate the protective effect of epimedium against ES by analyzing the molecular relationship between mitochondrial dynamics and steroidogenesis and to
Zhaoqing Zheng et al.
Journal of neurophysiology, 101(5), 2539-2549 (2009-03-06)
The cyclic AMP-dependent protein kinase (PKA) signaling pathway has been shown to be important in mechanisms of synaptic plasticity, although its direct and downstream signaling effects are not well understood. Using an in vitro model of eyeblink classical conditioning, we
The Chinese herbal medicine Dai-Zong-Fang promotes browning of white adipocytes in vivo and in vitro by activating PKA pathway to ameliorate obesity.
Xu, et al.
Frontiers in Pharmacology, 14, 1176443-1176443 (2023)
Qiushi Xu et al.
Journal of dairy science, 104(4), 4999-5008 (2021-02-09)
Preadipocyte proliferation and differentiation are critical for normal adipose tissue development, including achieving a mature phenotype, characterized by its ability to accumulate triacylglycerol and release fatty acids. In nonruminants, it is well known that all-trans retinoic acid (ATRA), the most-active
Gregory Segala et al.
Nature communications, 10(1), 1833-1833 (2019-04-25)
In response to extracellular signals, many signalling proteins associated with the plasma membrane are sorted into endosomes. This involves endosomal fusion, which depends on the complexes HOPS and CORVET. Whether and how their subunits themselves modulate signal transduction is unknown.

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