MilliporeSigma
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09-230

Sigma-Aldrich

Anti-phospho-Raptor (Thr706) Antibody

from rabbit, purified by affinity chromatography

Synonym(s):
P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, canine

species reactivity (predicted by homology)

mouse (based on 100% sequence homology), rat (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), horse (based on 100% sequence homology)

technique(s)

dot blot: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Gene Information

bovine ... Rptor(507056)
human ... RPTOR(57521)

General description

Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.

Specificity

This antibody recognizes Raptor phosphorylated at Thr706.

Immunogen

Epitope: Ser706
KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706.

Application

Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB.

Quality

Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Target description

~ 150 kDa

Physical form

Purified rabbit serum in PBS with 0.05% sodium azide.

Analysis Note

Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Quality

Enter Lot Number to search for Certificate of Quality (COQ).

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