MilliporeSigma
All Photos(2)

1.00020

Supelco

Acetone

for liquid chromatography LiChrosolv®

Synonym(s):
Dimethyl ketone, Propanone, 2-Propanone
Linear Formula:
CH3COCH3
CAS Number:
Molecular Weight:
58.08
Beilstein:
635680
MDL number:
EC Index Number:
200-662-2

vapor density

2 (vs air)

Quality Level

vapor pressure

184 mmHg ( 20 °C)

product line

LiChrosolv®

grade

isocratic

assay

≥99.8% (GC)

form

liquid

autoignition temp.

465 °C (DIN 51794)

potency

5800 mg/kg LD50, oral (Rat)
20000 mg/kg LD50, skin (Rabbit)

expl. lim.

13.2 %

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Acidity
≤0.0002 meq/g Alkalinity
≤0.05% Water

evapn. residue

≤2.0 mg/L

transmittance

335 nm, ≥50%
340 nm, ≥80%
350 nm, ≥98%

refractive index

n20/D 1.359 (lit.)

pH

5-6 (20 °C, 395 g/L in H2O)

capacity

1000  g/kg water absorbing capacity

bp

56 °C/760 mmHg (lit.)

mp

−94 °C (lit.)

transition temp

flash point <-20 °C

density

0.791 g/mL at 25 °C (lit.)

storage temp.

2-30°C

SMILES string

CC(C)=O

InChI

1S/C3H6O/c1-3(2)4/h1-2H3

InChI key

CSCPPACGZOOCGX-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

LiChrosolv® solvents show high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

Application

Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .
Intended for HPLC and UHPLC-MS applications, either as an extraction solvent or as a mobile phase.
Reported for use in LC–MS/MS investigations of:
  • blood plasma and serum samples fractionated on several chromatography sorbents[1][2]
  • peptides in animal biological samples[3]

Packaging

5 l in Aluminium Bottle
10 l in Barrel stainl. st.
1, 2.5, 4 l in Glass bottle

Features and Benefits

  • suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
  • specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
—ESI/APCI (+) < 2 ppb
—ESI/APCI (-) < 10 ppb
  • lowest impurity profile: for interference-free baselines (test 2)
  • microfiltered through 0.2 μm filter (test 3) to provide:
—a long lifespan to filters and mechanical parts of HPLC systems
—reduced risk of column clogging

  • packed in borosilicate glass bottles for minimized metal ion contaminations
  • lowest levels of trace metal impurities for a minimum metal ion adduct formation
—<5 ppb
  • lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

Preparation Note

Product filtered through a 0.2 μm filter

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

1.4 °F - closed cup

Flash Point(C)

-17.0 °C - closed cup

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Quality

Enter Lot Number to search for Certificate of Quality (COQ).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service