MilliporeSigma
All Photos(2)

1.00577

Supelco

Water

for headspace gas chromatography SupraSolv®

Linear Formula:
H2O
CAS Number:
Molecular Weight:
18.02
Beilstein:
2050024
MDL number:

Agency

according to Ph. Eur.
according to USP

Quality Level

vapor pressure

23 hPa ( 20 °C)

product line

SupraSolv®

form

liquid

technique(s)

GC-HS: suitable

impurities

≤1 μg/g Every residual solvent of class 1 acc. to ICH
≤10 μg/g Every residual solvent of class 2 acc. to ICH
≤50 μg/g Every residual solvent of class 3 acc. to ICH

evapn. residue

≤5 mg/L

refractive index

n20/D 1.34 (lit.)

pH

7 (20 °C)

bp

100 °C (lit.)

mp

0 °C (lit.)

density

1.000 g/mL at 3.98 °C (lit.)

storage temp.

2-30°C

SMILES string

O

InChI

1S/H2O/h1H2

InChI key

XLYOFNOQVPJJNP-UHFFFAOYSA-N

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This Item
1.153331.026991.03728
Water for headspace gas chromatography SupraSolv®

Supelco

1.00577

Water

Water for chromatography (LC-MS Grade) LiChrosolv®

Supelco

1.15333

Water

Water for gas chromatography SupraSolv®

Supelco

1.02699

Water

Water for UHPLC-MS LiChrosolv®

Supelco

1.03728

Water

vapor pressure

23 hPa ( 20 °C)

vapor pressure

23 hPa ( 20 °C)

vapor pressure

23 hPa ( 20 °C)

vapor pressure

23 hPa ( 20 °C)

form

liquid

form

liquid

form

liquid

form

liquid

technique(s)

GC-HS: suitable

technique(s)

LC/MS: suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

UHPLC: suitable

impurities

≤1 μg/g Every residual solvent of class 1 acc. to ICH, ≤10 μg/g Every residual solvent of class 2 acc. to ICH, ≤50 μg/g Every residual solvent of class 3 acc. to ICH

impurities

-

impurities

-

impurities

-

refractive index

n20/D 1.34 (lit.)

refractive index

n20/D 1.34 (lit.)

refractive index

n20/D 1.34 (lit.)

refractive index

n20/D 1.34 (lit.)

pH

7 (20 °C)

pH

7 (20 °C)

pH

7 (20 °C)

pH

7 (20 °C)

General description

SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all residual solvents defined by the ICH.

Analysis Note

residue on evaporation: ≤ 5 mg/l
GC/HS
Every residual solvent of class 1 acc. to ICH: ≤ 1 µg/g
Every residual solvent of class 2 acc. to ICH: ≤ 10 µg/g
Every residual solvent of class 3 acc. to ICH: ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1, 2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, N,N-dimethylacetamide, N,N-dimethy lformamide and dimethyl sulfoxide are not detected.

Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

No data available

Flash Point(C)

No data available


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