1.00887

Ethyl 4-hydroxybenzoate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, NF

• Synonym(s): Ethylparaben, Ethyl 4-hydroxybenzoate
• Empirical Formula (Hill Notation): C₉H₁₀O₃
• CAS Number: 120-47-8
• Molecular Weight: 166.17
• MDL number: MFCD00002353
• EC Index Number: 204-399-4

Properties

• Quality Level: 500
• Agency: BP; JP; NF; Ph. Eur.
• vapor pressure: 0.00012 hPa ( 25 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: 98.0-102.0% (HPLC)
• form: solid
• autoignition temp.: 495 °C
• pH: 4.5-5.5 (20 °C in H₂O, saturated solution)
• bp: 297 °C/1013 hPa (decomposition)
• mp: 115-118 °C
• application(s): ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
• InChI key: NUVBSKCKDOMJSU-UHFFFAOYSA-N

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable