MilliporeSigma
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1.00887

SAFC

Ethyl 4-hydroxybenzoate

EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, NF

Synonym(s):
Ethylparaben, Ethyl 4-hydroxybenzoate
Empirical Formula (Hill Notation):
C9H10O3
CAS Number:
Molecular Weight:
166.17
MDL number:
EC Index Number:
204-399-4

Quality Level

Agency

BP
JP
NF
Ph. Eur.

vapor pressure

0.00012 hPa ( 25 °C)

product line

EMPROVE® ESSENTIAL

assay

98.0-102.0% (HPLC)

form

solid

autoignition temp.

495 °C

pH

4.5-5.5 (20 °C in H2O, saturated solution)

bp

297 °C/1013 hPa (decomposition)

mp

115-118 °C

application(s)

ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI key

NUVBSKCKDOMJSU-UHFFFAOYSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Ethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

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Certificate of Quality

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What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials.

Material Qualification Dossier

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Quality Management Dossier

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Operational Excellence Dossier

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Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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