MilliporeSigma

1.02092

SAFC

tri-Calcium dicitrate tetrahydrate

EMPROVE® ESSENTIAL, USP, FCC, E 333

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Synonym(s):
tri-Calcium dicitrate tetrahydrate, Calcium(II) citrate, Tricalcium citrate
Empirical Formula (Hill Notation):
C12H10Ca3O14 · 4H2O
CAS Number:
Molecular Weight:
570.49
MDL number:
E Number:
E333
EC Index Number:
212-391-7

Agency

USP

Quality Level

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

pH

5-6 (20 °C, 25 g/L in H2O, slurry)

solubility

0.85 g/L

application(s)

pharmaceutical
solid formulation

storage temp.

2-30°C

InChI

1S/2C6H8O7.3Ca.4H2O/c2*7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;;;/h2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;4*1H2/q;;3*+2;;;;/p-6

InChI key

LNIZKKFWMDARJV-UHFFFAOYSA-H

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This Item
211183597341.06432
Calcium citrate tribasic tetrahydrate BioUltra, ≥98.0% (calc. on dry substance, KT)

Sigma-Aldrich

21118

Calcium citrate tribasic tetrahydrate

Premium Grade
tri-Sodium citrate dihydrate crystalline, EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, E 331

SAFC

1.06432

tri-Sodium citrate dihydrate

-
solubility

0.85 g/L

solubility

0.1 M HCl: 0.01 M at 20 °C, clear, colorless

solubility

-

solubility

-

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

2-30°C

Quality Level

500

Quality Level

-

Quality Level

200

Quality Level

500

agency

USP

agency

-

agency

-

agency

BP, JP, Ph. Eur., USP

reg. compliance

FCC

reg. compliance

-

reg. compliance

-

reg. compliance

-

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Calcium dicitrate is an organic calcium salt with a high calcium content, making it a highly economic calcium source for pharmaceutical as well as food applications. It also used as pH adjuster or buffer agent.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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