MilliporeSigma

1.02776

SAFC

Trehalose dihydrate

EMPROVE® EXPERT, Ph. Eur., ChP, NF, JP

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Synonym(s):
D-(+)-Trehalose dihydrate, 1-O-alpha-D-Glucopyranosyl-alpha-D-glucopyranoside, α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
Empirical Formula (Hill Notation):
C12H22O11 · 2H2O
CAS Number:
Molecular Weight:
378.33
Beilstein:
5322018
MDL number:
EC Index Number:
202-739-6

Agency

ChP
JP
NF
Ph. Eur.

Quality Level

product line

EMPROVE® EXPERT

form

solid

mp

96.5-97.5 °C

application(s)

liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
semi-solid formulation

storage temp.

no temp limit

SMILES string

[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

InChI key

DPVHGFAJLZWDOC-PVXXTIHASA-N

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This Item
62562590210PHR1344
Trehalose dihydrate EMPROVE® EXPERT, Ph. Eur., ChP, NF, JP

SAFC

1.02776

Trehalose dihydrate

Trehalose, Dihydrate Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro.

Millipore

625625

Trehalose, Dihydrate

D-(+)-Trehalose dihydrate suitable for microbiology, ≥99.0%, composed of two α-glucose units that is used as a protectant, stabilizer and to support proper folding

Millipore

90210

D-(+)-Trehalose dihydrate

Trehalose Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1344

Trehalose

form

solid

form

solid

form

powder

form

-

mp

96.5-97.5 °C

mp

-

mp

-

mp

-

storage temp.

no temp limit

storage temp.

15-25°C

storage temp.

-

storage temp.

2-30°C

Quality Level

500

Quality Level

100

Quality Level

200

Quality Level

300

agency

ChP

agency

-

agency

-

agency

traceable to Ph. Eur. Y0001172, traceable to USP 1673715

General description

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Trehalose is widely used in biomolecule formulation as a stabilizing agent.
Trehalose dihydrate Emprove® Expert is low in endotoxins and bioburden, making it the right choice for your high-risk applications.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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