1.03132

1,4-Dioxane

for liquid chromatography LiChrosolv^®

• Synonym(s): 1,4-Dioxane, Glycolethylether, 1,4-Diethylene dioxide, 1,4-Dioxacyclohexane
• Empirical Formula (Hill Notation): C₄H₈O₂
• CAS Number: 123-91-1
• Molecular Weight: 88.11
• MDL number: MFCD00006571
• EC Index Number: 204-661-8

Properties

• vapor pressure: 41 hPa ( 20 °C)
• Quality Level: 100
• product line: LiChrosolv^®
• grade: isocratic
• assay: ≥99.8% (GC)
• form: liquid
• autoignition temp.: 300 °C
• potency: 5200 mg/kg LD₅₀, oral (Rat); 7600 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.7-25.2 % (v/v)
• application(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity; ≤0.0002 meq/g Alkalinity; ≤0.02% Water
• pH: 6-8 (20 °C, 500 g/L in H₂O)
• bp: 101.5 °C/1013 hPa
• mp: 12 °C
• transition temp: flash point 11 °C
• density: 1.03 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
• InChI key: RYHBNJHYFVUHQT-UHFFFAOYSA-N

Description

General description

With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.

Analysis Note

Purity (GC): ≥ 99.8 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.02 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Transmission (at 245 nm): ≥ 50 %
Transmission (at 270 nm): ≥ 80 %
Transmission (from 300 nm): ≥ 98 %
Filtered by 0.2 µm filter

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H319 - H335 - H351
• Precautionary Statements: P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH019 - EUH066
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 51.8 °F - closed cup
• Flash Point(C): 11 °C - closed cup