1.04008

Supelco

Formamide

EMPLURA®

Synonym(s):
Amide C1, Formic amide, Formic acid amide, Methane amide
Linear Formula:
HCONH2
CAS Number:
Molecular Weight:
45.04
Beilstein/REAXYS Number:
505995
MDL number:
EC Index Number:
200-842-0

storage conditions

Store at +2°C to +25°C.

Quality Level

vapor density

1.55 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)
30 mmHg ( 129 °C)

assay

≥99% (N)

form

liquid

autoignition temp.

932 °F

potency

5325 mg/kg LD50, oral (Rat)
17000 mg/kg LD50, skin (Rabbit)

expl. lim.

2.7-19.0 % (v/v)

application(s)

hybridization: suitable

impurities

≤0.3% Water (Karl Fischer)

refractive index

n20/D 1.447 (lit.)

pH

8-10 (20 °C, 200 g/L in H2O)

bp

210 °C (lit.)

mp

2-3 °C (lit.)

transition temp

flash point 175 °C

density

1.134 g/mL at 25 °C (lit.)

storage temp.

15-25°C

SMILES string

NC=O

InChI

1S/CH3NO/c2-1-3/h1H,(H2,2,3)

InChI key

ZHNUHDYFZUAESO-UHFFFAOYSA-N

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Application

Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization temperatures.

Analysis Note

Assay (N; Kjeldahl): ≥ 99.0 %
Identity (IR): passes test
Density (d 20 °C/ 4 °C): 1.132 - 1.135
Water (according to Karl Fischer): ≤ 0.3 %

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

hazcat

Carc. 2 - Repr. 1B - STOT RE 2 Oral

Target Organs

Blood

storage_class_code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK Germany

WGK 1

Flash Point(F)

305.6 °F

Flash Point(C)

152 °C

Certificate of Analysis

Certificate of Origin

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