MilliporeSigma

104132

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Cellvento® ModiFeed Prime COMP

chemically defined cell culture feed

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Quality Level

description

shipped with cooling packs

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

storage temp.

2-8°C

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technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable (suspension)

technique(s)

cell culture | mammalian: suitable (suspension)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

500

Quality Level

500

Quality Level

500

Quality Level

500

description

shipped with cooling packs

description

-

description

-

description

-

General description

Cellvento® ModiFeed Prime COMP is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode. This single feed is highly concentrated, allowing for a reduction in volume of feed added to the medium thereby increasing product yield.The formulation has been specifically designed to provide increased process control and decreased complexity. Exclusion of glucose from the formulation allows for fed-batch process dictated regulation of this critical parameter. As a one-part feed, containing modified amino acids and amino acid derivatives, the complexity of hydration, storage, and feeding is drastically reduced.

Application

Cellvento® ModiFeed Prime COMP has been developed as a feed supplement to be used in combination with the production media, Cellvento® 4CHO COMP and EX-CELL® Advanced CHO, during fed-batch manufacturing processes. It has been designed to support optimal cell growth and high productivity of suspension CHO cell lines such as CHO-K1, CHO-DG44, CHO-S and CHO-GS, including cell lines derived using the CHOZN® platform Fed-batch (batch, perfusion)

Quantity

Formulated to contain 131.6 grams of powder per liter of medium.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
CHOZN is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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Articles

Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

Optimizing Upstream Media and Feeds in Bioprocessing

Why optimize your upstream bioprocess media and feed? This article discusses the why and how of optimizing your media and feed to maximize cell viability and productivity.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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