MilliporeSigma
All Photos(3)

Documents

1.04390

Supelco

n-Heptane

greener alternative

for liquid chromatography LiChrosolv®

Sign Into View Organizational & Contract Pricing

Synonym(s):
Heptane
Linear Formula:
CH3(CH2)5CH3
CAS Number:
Molecular Weight:
100.20
Beilstein/REAXYS Number:
1730763
MDL number:
EC Index Number:
205-563-8

vapor density

3.5 (vs air)

Quality Level

vapor pressure

40 mmHg ( 20 °C)
83 mmHg ( 37.7 °C)

product line

LiChrosolv®

grade

isocratic

assay

≥99.3% (GC)

form

liquid

autoignition temp.

433 °F

potency

>5000 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rabbit)

expl. lim.

7 %

greener alternative product characteristics

Safer Solvents and Auxiliaries
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Acidity
≤0.0002 meq/g Alkalinity
≤0.005% Water

evapn. residue

≤2.0 mg/L

transmittance

210 nm, ≥50%
220 nm, ≥80%
245 nm, ≥98%

refractive index

n20/D 1.387 (lit.)

bp

98 °C (lit.)

mp

−91 °C (lit.)

transition temp

flash point -4 °C

solubility

0.05 g/L

density

0.684 g/mL at 25 °C (lit.)

greener alternative category

storage temp.

2-30°C

SMILES string

CCCCCCC

InChI

1S/C7H16/c1-3-5-7-6-4-2/h3-7H2,1-2H3

InChI key

IMNFDUFMRHMDMM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
1.043601.043661.04379
n-Heptane for liquid chromatography LiChrosolv®

1.04390

n-Heptane

n-Heptane for gas chromatography ECD and FID SupraSolv®

1.04360

n-Heptane

n-Heptane for spectroscopy Uvasol®

1.04366

n-Heptane

n-Heptane for analysis EMSURE® Reag. Ph Eur

1.04379

n-Heptane

grade

isocratic

grade

-

grade

-

grade

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

300

solubility

0.05 g/L

solubility

-

solubility

0.05 g/L

solubility

-

form

liquid

form

liquid

form

liquid

form

liquid

technique(s)

HPLC: suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

UV/Vis spectroscopy: suitable

technique(s)

-

General description

LiChrosolv® solvents exhibit high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them suitable for reproducible separations.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Heptane is an environmentally preferable solvent compared to hexane and thus align with "Safer Solvents and Auxiliaries". Click here for more information.

Application

Intended for U/HPLC and LC-MS/MS applications.
Also reported for use as a component of extraction mixture in screening drugs of abuse in urine samples by GC-MS.

Features and Benefits

  • suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
  • specified quality in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses in all important MS modes (test 1)
—ESI/APCI (+) < 2 ppb
—ESI/APCI (-) < 10 ppb
  • lowest impurity profile: for interference-free baselines (test 2)
  • microfiltered through 0.2 μm filter (test 3) to provide:
—a long lifespan to filters and mechanical parts of HPLC systems
—reduced risk of column clogging
  • packaged in borosilicate glass bottles for minimized contamination with metal ions
  • lowest levels of trace metal impurities to minimize metal ion adduct formation
—<5ppb
  • lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Purity (GC): ≥ 99.3 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.005 %
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Transmission (at 210 nm): ≥ 50 %
Transmission (at 220 nm): ≥ 80 %
Transmission (from 245 nm): ≥ 98 %
Filtered by 0.2 µm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

24.8 °F

flash_point_c

-4 °C


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 6

1 of 6

Heptane HPLC Plus, for HPLC, GC, and residue analysis, 99%

Sigma-Aldrich

650536

Heptane

Heptane Technical

Supelco

HX0090

Heptane

Heptane suitable for HPLC, &#8805;96%

Sigma-Aldrich

592579

Heptane

Heptane Meets Reagent Specifications for testing USP/NF monographs OmniSolv&#174;

Supelco

HX0078

Heptane

Heptane ReagentPlus&#174;, 99%

Sigma-Aldrich

H2198

Heptane

Heptane-1-13C 99 atom % 13C

Sigma-Aldrich

492728

Heptane-1-13C

LC-MS/MS with atmospheric pressure chemical ionisation to study the effect of UV treatment on the formation of vitamin D3 and sterols in plants
Japelt RB, et al.
Food Chemistry, 129(1), 217-225 (2011)
Intoxication caused by new psychostimulants: analytical methods to disclose acute and chronic use of benzofurans and ethylphenidate
Barcelo B, et al.
International Journal of Legal Medicine, 131(6), 1543-1553 (2017)

Articles

HPTLC separation followed by UV detection of the bitter acid content in various hop samples.

Protocols

HPTLC was used to analyze caffeine in coffee. Filtration of coffee through a PTFE syringe filter was the only sample preparation. Quantitation was conducted with a TLC scanner.

Thin layer chromatography coupled with mass spectrometry does not require substantial sample preparation. Energy drinks can be applied without dilution directly onto the TLC plate.

HPTLC–MS analysis of quinine in tonic water and caffeine in coffee and cola drinks. Tonic and cola drinks decarbonized through ultrasonication, and coffee extracted through PTFE filter.

The modern thin-layer chromatography (TLC) offers advantages also in the field of cosmetics to quickly and simultaneously analyze samples with densitometric detection.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service