1.06007

Methanol

≥99.9% (GC), gradient grade, suitable for HPLC, LiChrosolv^®, reag. Ph. Eur.

• Synonym(s): Methyl alcohol
• Linear Formula: CH₃OH
• CAS Number: 67-56-1
• Molecular Weight: 32.04
• Beilstein/REAXYS Number: 1098229
• MDL number: MFCD00004595
• UNSPSC Code: 12191502
• EC Index Number: 200-659-6
• NACRES: NA.03
• assay: ≥99.9% (GC)
• technique(s): HPLC: suitable
• bp: 64.7 °C (lit.)
• vapor pressure: 128 hPa ( 20 °C); 410 mmHg ( 50 °C); 97.68 mmHg ( 20 °C)

Properties

• Product Name: Methanol, gradient grade for liquid chromatography LiChrosolv^® Reag. Ph Eur
• grade: gradient grade; gradient grade
• Quality Level: 200
• agency: reag. Ph. Eur.
• vapor density: 1.11 (vs air)
• vapor pressure: 128 hPa ( 20 °C); 410 mmHg ( 50 °C); 97.68 mmHg ( 20 °C)
• product line: LiChrosolv^®
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 725 °F
• potency: 5628 mg/kg LD₅₀, oral (Rat); 17100 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 36 %
• technique(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity; ≤0.0002 meq/g Alkalinity; ≤0.02% Water
• evapn. residue: ≤2.0 mg/L
• color: APHA: ≤10
• transmittance: 210 nm, ≥20%; 220 nm, ≥60%; 230 nm, ≥75%; 235 nm, ≥83%; 250 nm, ≥95%; 260 nm, ≥98%
• refractive index: n20/D 1.329 (lit.)
• kinematic viscosity: 0.54-0.59 cSt(20 °C)
• bp: 64.7 °C (lit.)
• mp: −98 °C (lit.)
• transition temp: flash point 9.7 °C
• density: 0.791 g/mL at 25 °C (lit.)
• UV absorption: λ: 225 nm A_max: ≤0.170
• format: neat
• storage temp.: 2-30°C
• SMILES string: CO
• InChI: 1S/CH4O/c1-2/h2H,1H3
• InChI key: OKKJLVBELUTLKV-UHFFFAOYSA-N

Description

General description

With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.

Application

Methanol is used as a solvent:

• In the mobile phase to separate mercury species on a Zorbax C18 reverse phase column. [1]
• To wash the cartridges and as an eluent to extract the analytes during the solid-phase extraction (SPE) process. [2]

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Evaporation Number: 1.9

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Evaporation residue: ≤ 2.0 mg/l
Water: ≤ 0.02 %
Color: ≤ 10 Hazen
Density (d 20 °C/20 °C): 0.791 - 0.793
Boiling point: 64 - 65 °C
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Gradient grade (at 235 nm): ≤ 2.0 mAU
Gradient grade (at 254 nm): ≤ 1.0 mAU
Fluorescence (as quinine at 254 nm): ≤ 1.0 ppb
Fluorescence (as quinine at 365 nm): ≤ 0.5 ppb
Transmission (at 210 nm): ≥ 20 %
Transmission (at 220 nm): ≥ 60 %
Transmission (at 230 nm): ≥ 75 %
Transmission (at 235 nm): ≥ 83 %
Transmission (at 250 nm): ≥ 95 %
Transmission (from 260 nm): ≥ 98 %
Absorbance (at 225 nm): ≤ 0.170
Filtered by 0.2 µm filter.
Suitable for UPLC / UHPLC /Ultra HPLC - instruments.
Conforms to Methanol R1 and R2 according to Reag. Ph Eur;
conforms to the requirements of ACS for liquid chromatography suitability.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS06,GHS08
• signalword: Danger
• hcodes: H225,H301 + H311 + H331,H370
• pcodes: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• target_organs: Eyes,Central nervous system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 2
• flash_point_f: 49.5 °F - closed cup
• flash_point_c: 9.7 °C - closed cup