1.06022
Sodium dodecyl sulfate
for biochemistry 10% in H₂O
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Dodecyl sulfate sodium salt, SDS, Lauryl sulfate sodium salt, Dodecyl sodium sulfate
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General description
Dodecyl sulfate sodium or sodium dodecyl sulfate (SDS) is an ionic detergent comprising a polar sulfate head group and a hydrophobic 12-carbon chain.
Biochem/physiol Actions
Dodecyl sulfate sodium or sodium dodecyl sulfate (SDS) combines effectively with the positively charged and hydrophobic residues of proteins using sulfate groups and alkyl chains. This detergent is very valuable in the field of structural biology and protein folding/unfolding studies. SDS can initiate the generation of α-helices in a protein structure. It stimulates cooperative unfolding in proteins like bovine serum albumin (BSA), β-lactoglobulin, α-lactalbumin, and hen egg-white lysozyme structures at elevated concentrations.
Analysis Note
Assay (two-phase titration): 9.8 - 10.2 %
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Protocols
Protocol for sample preparation for cell lysis and efficient protein extraction from cultured tissues and cells for subsequent Western blotting.
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