1.06573

di-Sodium hydrogen phosphate dodecahydrate

crystalline, EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP

• Synonym(s): Sodium phosphate dibasic dodecahydrate, Sodium monohydrogen phosphate, Sodium phosphate dibasic, sec-Sodium phosphate, Disodium hydrogen phosphate dodecahydrate, Disodium phosphate, di-Sodium hydrogen phosphate dodecahydrate
• Linear Formula: Na₂HPO₄ · 12H₂O
• CAS Number: 10039-32-4
• Molecular Weight: 358.14
• MDL number: MFCD00149181
• EC Index Number: 231-448-7

Properties

• Agency: BP; ChP; JP; Ph. Eur.; USP
• Quality Level: 500
• product line: EMPROVE^® ESSENTIAL
• form: crystalline; solid
• pH: 9.0-9.3 (20 °C, 50 g/L in H₂O)
• solubility: 218 g/L
• density: 1.52 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-8°C
• SMILES string: O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P.12H2O/c;;1-5(2,3)4;;;;;;;;;;;;/h;;(H3,1,2,3,4);12*1H2/q2*+1;;;;;;;;;;;;;/p-2
• InChI key: DGLRDKLJZLEJCY-UHFFFAOYSA-L

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate dodecahydrate is typically used as a phosphate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Packaging

1, 5 kg in PE bottle

25 kg in PE bag

25 kg in PE bag (in PE square drum)

25 kg in double PE bag (DPES in carton)

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable