MilliporeSigma

1.07478

SAFC

1,2-Propanediol

EMPROVE® EXPERT, Ph. Eur., BP, USP

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Synonym(s):
1,2-Propanediol, 1,2-Propylene glycol
Linear Formula:
CH3CH(OH)CH2OH
CAS Number:
Molecular Weight:
76.09
MDL number:
EC Index Number:
200-338-0

Agency

BP
Ph. Eur.
USP

Quality Level

vapor pressure

0.11 hPa ( 20 °C)

product line

EMPROVE® EXPERT

Assay

≥99.5% (GC)

form

liquid

autoignition temp.

371 °C

expl. lim.

2.4-17.4 % (v/v)

refractive index

n20/D 1.43

pH

6-8 (20 °C, 100 g/L in H2O)

bp

188 °C/1013 hPa

mp

-59 °C

transition temp

flash point 99 °C

density

1.04 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
parenterals
parenterals
pharmaceutical
semi-solid formulation

storage temp.

2-30°C

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

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This Item
82281PX169016033
1,2-Propanediol EMPROVE® EXPERT, Ph. Eur., BP, USP

SAFC

1.07478

1,2-Propanediol

1,2-Propanediol tested according to Ph. Eur.

Sigma-Aldrich

82281

1,2-Propanediol

1,2-Propanediol

Supelco

PX1690

1,2-Propanediol

1,2-Propanediol meets analytical specification of Ph. Eur., BP, USP, ≥99.5%

Sigma-Aldrich

16033

1,2-Propanediol

assay

≥99.5% (GC)

assay

-

assay

≥98% (GC)

assay

≥99.5%

form

liquid

form

viscous liquid

form

liquid

form

liquid

autoignition temp.

371 °C

autoignition temp.

779 °F

autoignition temp.

-

autoignition temp.

779 °F

expl. lim.

2.4-17.4 % (v/v)

expl. lim.

12.5 %

expl. lim.

-

expl. lim.

12.5 %

refractive index

n20/D 1.43

refractive index

n20/D 1.432 (lit.)

refractive index

n20/D 1.43

refractive index

n20/D 1.431-1.433, n20/D 1.432 (lit.)

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Propylene glycol is used as solvent in a variety of liquid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

219.2 °F - closed cup

Flash Point(C)

104 °C - closed cup


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