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1.08121

Bromocresol green

pH indicator, ACS, Reag. Ph Eur

Synonym(s):

Bromocresol green, 3,3′,5,5′-Tetrabromo-m-cresolsulfonphthalein, BCG

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1 g
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$239.00
5 g
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$274.00
25 g
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$684.00

About This Item

Empirical Formula (Hill Notation):
C21H14Br4O5S
CAS Number:
Molecular Weight:
698.01
UNSPSC Code:
41116100
EC Index Number:
200-972-8
NACRES:
NB.21
MDL number:

$239.00


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Product Name

Bromocresol green, indicator ACS,Reag. Ph Eur

grade

ACS reagent

Quality Level

agency

reag. Ph. Eur.

form

solid

loss

≤3% loss on drying, 110°C

visual transition interval

3.8-5.4, yellow-green to blue

mp

217-218 °C

bulk density

350 kg/m3

storage temp.

no temp limit

SMILES string

[S]1(=O)(=O)OC(c4c1cccc4)(c3c(c(c(c(c3)Br)O)Br)C)c2c(c(c(c(c2)Br)O)Br)C

InChI

1S/C21H14Br4O5S/c1-9-12(7-14(22)19(26)17(9)24)21(13-8-15(23)20(27)18(25)10(13)2)11-5-3-4-6-16(11)31(28,29)30-21/h3-8,26-27H,1-2H3

InChI key

FRPHFZCDPYBUAU-UHFFFAOYSA-N

Application



  • Sensitive and selective spectrophotometric assay of piroxicam in pure form, capsule and human blood serum samples via ion-pair complex formation.: This study presents a sensitive spectrophotometric method for determining piroxicam in various forms by forming an ion-pair complex with bromocresol green. This method enhances the accuracy and selectivity of piroxicam assays, providing valuable applications in pharmaceutical analysis and clinical diagnostics (Alizadeh & Keyhanian, 2014).

  • A high-throughput colorimetric assay to measure the activity of glutamate decarboxylase.: Bromocresol green is utilized in a high-throughput colorimetric assay to measure the activity of glutamate decarboxylase. This assay is crucial for biochemical studies involving enzyme kinetics and could be applied in drug discovery and metabolic engineering research (Yu et al., 2011).

  • Spectrophotometric and HPLC determinations of anti-diabetic drugs, rosiglitazone maleate and metformin hydrochloride, in pure form and in pharmaceutical preparations.: The use of bromocresol green in spectrophotometric and HPLC methods enhances the detection and quantification of anti-diabetic drugs. This research is vital for ensuring the quality and efficacy of pharmaceutical products (Onal, 2009).

  • Spectrophotometric determination of lamotrigine in pharmaceutical preparations and urine by charge-transfer complexation.: Bromocresol green is employed in the spectrophotometric determination of lamotrigine, facilitating the analysis of this antiepileptic drug in pharmaceutical and biological samples. This application is essential for therapeutic drug monitoring and pharmaceutical quality control (Alizadeh et al., 2008).


Analysis Note

Transition range: pH 3.8 - pH 5.4yellowish green - blue
Appearance of solution: passes test
Loss on drying (110 °C): ≤ 3
Transition range (according to ACS): passes test
Sensitivity test: passes test

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Show Differences

1 of 1

This Item
11435903-377040-1010
loss

≤3% loss on drying, 110°C

loss

-

loss

-

loss

-

storage temp.

no temp limit

storage temp.

room temp

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

-

form

solid

form

powder

form

-

form

liquid

mp

217-218 °C

mp

225 °C (dec.) (lit.)

mp

225 °C (dec.) (lit.)

mp

-

visual transition interval

3.8-5.4, yellow-green to blue

visual transition interval

3.8, yellow(passes test), 3.8-5.4, yellow to blue(passes test), 4.5, green, 5.4, blue

visual transition interval

-

visual transition interval

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
108121000104022536100678
108121000504022536100685
108121002504022536100692

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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