1191

Adenosine 5′-Triphosphate, Disodium Salt

• Synonym(s): Adenosine 5′-Triphosphate, Disodium Salt, ATP, 2Na
• Empirical Formula (Hill Notation): C₁₀H₁₄N₅O₁₃P₃ · 2Na
• CAS Number: 987-65-5
• Molecular Weight: 551.14
• UNSPSC Code: 12352208
• NACRES: NA.51
• MDL number: MFCD00080339
• Assay: ≥95% (HPLC)
• Form: solid
• Solubility: water: 20 mg/mL
• Storage temp.: −20°C

Properties

• description: RTECS - AU7417000; Merck USA index - 14, 155
• Quality Level: 100
• assay: ≥95% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic)
• color: white
• solubility: water: 20 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].[P](=O)([O-])(O[P](=O)(O[P](=O)([O-])O)O)OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)[n]2c3ncnc(c3nc2)N
• InChI: 1S/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChI key: TTWYZDPBDWHJOR-IDIVVRGQSA-L

Description

General description

Coenzyme involved in the transfer of phosphate bond energy.

Application

• Asynchronising five-fold symmetry sequence for better homonuclear polarisation transfer in magic-angle-spinning solid-state NMR.: This study highlights the use of Adenosine 5′-Triphosphate, Disodium Salt (ATP) in enhancing nuclear magnetic resonance (NMR) spectroscopy techniques, which is pivotal in structural biochemistry and the study of molecular dynamics (Arunachalam et al., 2023).


• Insights into the conversion of dissolved organic phosphorus favors algal bloom, arsenate biotransformation and microcystins release of Microcystis aeruginosa.: This research utilizes ATP as a phosphorus source in studies of algal blooms, offering significant insights into environmental biochemistry and the biotransformation processes that impact water quality and ecosystem health (Zhang et al., 2023).


• Overview of Portable Assays for the Detection of Mycotoxins, Allergens, and Sanitation Monitoring.: ATP is utilized in the development of portable assays for rapid on-site testing in food safety and public health, demonstrating its versatility and essential role in biochemical assays aimed at improving global health outcomes (Sarver et al., 2021).


• Organic Phosphorous and Calcium Source Induce the Synthesis of Yolk-Shell Structured Microspheres of Calcium Phosphate with High-Specific Surface Area: Application in HEL Adsorption.: This study illustrates the application of ATP in synthesizing advanced materials for biomedical applications, specifically in the development of high-surface-area microspheres for therapeutic protein adsorption (Cao et al., 2020).


• Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity.: ATP′s role is investigated in cellular signaling pathways involved in inflammation and cardiovascular disease, providing crucial insights into the pathophysiology of atherosclerosis and potential therapeutic targets (Jiang et al., 2019).

Preparation Note

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 2-3 h at 4°C or for up to 3 months at -70°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2