MilliporeSigma

1.20093

Millipore

Eshmuno® CP-FT Resin

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Synonym(s):
Eshmuno® CP-FT

Quality Level

ligand

(Sulfoisobutyl)

sterility

sterile (Caustic Stable)

product line

Eshmuno®

form

resin

specific analyte(s)

MAbs

parameter

400 cm/hr flow rate
8 bar max. pressure

matrix active group

polymer, polyvinyl ether

mean particle size

50 μm

capacity

70 mg binding capacity (lysozyme/ml of resin)

transition temp

flash point 35 °C

separation technique

cation exchange
strong cation exchange

storage temp.

2-30°C

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Eshmuno® CP-FT Resin

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Eshmuno® CP-FT Resin MiniChrom Column Eshmuno® CP-FT, volume 5 mL, prepacked column

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1.25169

Eshmuno® CP-FT Resin

parameter

400 cm/hr flow rate, 8 bar max. pressure

parameter

500 cm/hr flow rate, 8 bar max. pressure

parameter

1000 cm/hr flow rate, 8 bar max. pressure

parameter

≤8 bar pressure, 400 cm/hr max. flow rate

matrix active group

polymer, polyvinyl ether

matrix active group

polymer, polyvinyl ether

matrix active group

polymer, polyvinyl ether

matrix active group

Polyvinyl Ether

capacity

70 mg binding capacity (lysozyme/ml of resin)

capacity

120 mg binding capacity (lysozyme/ml of resin)

capacity

50 mg binding capacity (pIgG/ml of resin)

capacity

~70 mL, resin binding capacity

separation technique

cation exchange, strong cation exchange

separation technique

strong cation exchange

separation technique

mixed mode

separation technique

-

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

2-30°C

storage temp.

15-25°C

General description

Cation exchange resin specifically developed for the flow-through removal of aggregates using frontal chromatography

Features and Benefits

Eshmuno® CP-FT chromatography resin enables:

  • Superior flow-through removal of mAb aggregates
  • High product recoveries at high mass loadings
  • Significant reduction in resin and buffer volume
  • Smaller manufacturing footprint (smaller columns, buffer tanks, etc.)
  • Low salt process conditions eliminate the need for dilution before subsequent ion exchange steps
  • Significant reduction in processing volumes improves virus filtration and ultrafiltration processing economics
  • Rigid base bead enables higher flow rates and easier column packing
  • Strong chemical stability
  • Compatibility with 1 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl and storage solutions 0.1 M NaOH

Packaging

  • 1.20093.0100: Eshmuno® CP-FT Resin 100 ml
  • 1.20093.0010: Eshmuno® CP-FT Resin 10 ml
  • 1.20093.0500: Eshmuno® CP-FT Resin 500 ml
  • 1.20093.5000: Eshmuno® CP-FT Resin 5 L
Plastic bottle

Legal Information

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Flame

Signal Word

Warning

Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

95.0 °F

Flash Point(C)

35 °C


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