12-123

PKC Substrate Peptide

Name: PKC Substrate Peptide
Brand: MM
Price: 295 USD
Availability: InStock

PKC Substrate Peptide primarily used in Kinase Assays.

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1 MG

$295.00

Estimated to ship onFebruary 06, 2026Details

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About This Item

UNSPSC Code:

12352200

NACRES:

NA.42

eCl@ss:

32160405

Key Documents

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Product Name

PKC Substrate Peptide, PKC Substrate Peptide primarily used in Kinase Assays.

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_002737.2

UniProt accession no.

P17252

shipped in

wet ice

Quality Level

100

Gene Information

human ... PRKCA(5578)

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This Item	12-152	12-340	12-459
Sigma-Aldrich 12-123 PKC Substrate Peptide	Sigma-Aldrich 12-152 PKA Substrate Peptide	Sigma-Aldrich 12-340 Akt/SGK Substrate Peptide	Sigma-Aldrich 12-459 IKK Substrate Peptide
technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)	technique(s) activity assay: suitable (kinase)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
Gene Information human ... PRKCA(5578)	Gene Information -	Gene Information -	Gene Information human ... CHUK(1147)
shipped in wet ice	shipped in wet ice	shipped in dry ice	shipped in dry ice
UniProt accession no. P17252	UniProt accession no. P17612	UniProt accession no. P31749	UniProt accession no. O15111
manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®

Analysis Note

routinely evaluated in an enzyme assay using PKC (14-115)

Biochem/physiol Actions

Protein Target: PKC

Target Sub-Family: AGC

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Physical form

Lyophilized powder

Preparation Note

2 years at 4°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Identification of two essential phosphorylated threonine residues in the catalytic domain of Mekk1. Indirect activation by Pak3 and protein kinase C.

Y L Siow et al.

The Journal of biological chemistry, 272(12), 7586-7594 (1997-03-21)

The 78-kDa protein kinase Mekk1 plays an important role in the stress response pathway that involves the activation of downstream kinases Sek1 and stress-activated protein kinase/c-Jun NH2-terminal kinase. Conserved serine and threonine residues located between the kinase subdomains VII and

Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha.

L M Neri et al.

The Journal of biological chemistry, 273(45), 29738-29744 (1998-10-29)

It is well established that an independent inositide cycle is present within the nucleus, where it is involved in the control of cell proliferation and differentiation. Previous results have shown that when Swiss 3T3 cells are treated with insulin-like growth

A synthetic peptide substrate for selective assay of protein kinase C.

I Yasuda et al.

Biochemical and biophysical research communications, 166(3), 1220-1227 (1990-02-14)

Among various phosphate acceptor proteins and peptides so far tested, a synthetic peptide having the sequence surrounding Ser(8) of myelin basic protein, Gln-Lys-Arg-Pro-Ser(8)-Gln-Arg-Ser-Lys-Tyr-Leu, (MBP4-14), is the most specific and convenient substrate which can be used for selective assay of protein

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