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137116

SAFC

L-Cysteine S-sulfate sodium salt sesquihydrate

EMPROVE® EXPERT

Synonym(s):
L-Cysteine S-sulfate sodium salt sesquihydrate, SCys, Sulfo-Cysteine, S-Sulfocysteine
Empirical Formula (Hill Notation):
C3H6NNaO5S2 · 1.5H2O
CAS Number:
Molecular Weight:
250.23

Quality Level

biological source

synthetic

product line

EMPROVE® EXPERT

form

powder or crystals

packaging

pkg of 1 kg (1371161000)
pkg of 100 g (1371160100)
pkg of 5 kg (1371165000)

solubility

water: soluble (Up to 1.3M (room temp))

suitability

suitable for manufacturing use (cell culture media)

storage temp.

room temp

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General description

Modified amino acids are inhouse manufactured amino acid derivatives with specific properties enabling the intensification of cell culture processes.

Together with the companion product Phospho-L-Tyrosine disodium Salt disodium salt, the new modified amino acid S-Sulfocysteine sodium salt can be used as replacement for cysteine to generate highly concentrated, neutral pH feeds. Both modified amino acids eliminate the need for alkaline feeds, which are normally applied to ensure solubility and stability of the unmodified amino acids tyrosine and cysteine.

Features and Benefits

  • Reduced complexity in fed-batch process
  • High concentrations of modified cysteine in main feeds at neutral pH
  • Prevention of caustic shocks in the bioreactor due to high pH feeds
  • More convenient preparation process with less contamination risks
  • Reduction of recombinant protein fragmentation and decrease in trisulfide bond content
  • Higher feed stability at room temperature

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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