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MilliporeSigma

137666

SAFC

Ethylene Glycol Emprove® Evolve

CIP (cleaning in place)

Pharma Manufacturing

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About This Item

UNSPSC Code:
12352137
Pricing and availability is not currently available.

agency

CIP (cleaning in place)

Quality Level

vapor pressure

0.053 hPa ( 20 °C)

assay

≥99.5% (GC)

form

liquid

autoignition temp.

410 °C

expl. lim.

3.2-15.3 %

impurities

≤0.00002% Chloride (CI)
≤0.001% Acidity (as CH3COOH)

pH

6-7.5 (20 °C, 100 g/L)

bp

197.6 °C/1013 hPa

mp

-14--10 °C

transition temp

flash point 111 °C

density

1.11 g/cm3 at 20 °C

application(s)

pharma/biopharma processes

storage temp.

2-30°C

General description

The new Ehtylene Glycol Emprove® Evolve meets the increasing quality requirements of of the biopharma industry for cleaning and storage of protein A resin.
We offer a range of high quality critical raw materials plus the documentation and expertise to help our customers meet stringent regulatory requirements. Our SAFC® portfolio of high-quality products withstands strict quality control procedures.

Application

Ethylene Glycol EMPROVE® Evolve meets the increasing quality requirements of the biopharma industry for cleaning and storage of protein A resin in downstream processes.
This chemical is used in the downstream process for the cleaning and storage of protein A resin.

Features and Benefits

Ethylene Glycol Emprove® Evolve cleaning and storage chemical can increase the lifetime of our Eshmuno® A resin as well as other protein A resins.

Packaging

Packsizes:
  • 1376661000: 1 L
  • 1376669025: 25 L
  • 1376669950: 950 L

Other Notes

More than 100% increase in column lifetime was achieved using a mixture of 20 % Ethylene Glycol and 0.1M NaOH solution. As a comparison, using traditional 0.1M solution resulted in an 80 % drop after just 250 cycles compared to an impressive 600 cycles using Ethylene Glycol Emprove® Evolve and 0.1M NaOH solution.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation markHealth hazard

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

target_organs

Kidney

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

239.0 °F - open cup

flash_point_c

115 °C - open cup


What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

Free of charge - Sign in to download

Material Qualification Dossier

Free of charge - Sign in to download

Quality Management Dossier (Open Access)

Free of charge - Sign in to download

Operational Excellence Dossier

Available by subscription or for a fee

Operational Excellence Dossier

Available by subscription or for a fee

Learn more about the benefits an Emprove® Program subscription can provide
Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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