1.41350

SAFC

Polyvinyl alcohol

4-88, EMPROVE® Essential, Ph. Eur., USP, JPE

Synonym(s):
PVA, PVOH, Poly(vinyl alcohol)
Linear Formula:
[-CH2CHOH-]n
CAS Number:
MDL number:

storage conditions

Store at +15°C to +25°C.

Agency/Method

JPE
Ph. Eur.
USP

Quality Level

description

EMPROVE® ESSENTIAL Ph Eur,USP,JPE

product line

EMPROVE® Essential

form

dry powder

potency

>2000 mg/kg LD50, oral (Rat)

mp

160-240 °C

bulk density

400‑670 kg/m3

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyvinyl alcohol 4-88 is a synthetic, bio-compatible, toxicologically safe, and multi-compendial polymer. It is part of a portfolio spanning a wide range of pharmaceutical grade polyvinyl alcohols of different viscosities, hydrolysis grades and molecular weights and is well suited for a broad variety of pharmaceutical applications, including solid, liquid, and semi-solid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials.

Material Qualification Dossier

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Quality Management Dossier

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Operational Excellence Dossier

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Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

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