Skip to Content
MilliporeSigma

14-309

PCAF Protein, Active, 50 µg

PCAF recombinant GST fusion protein, for use in Histone Acetyltransferase Assays. (HAT).

Slide 1 of 1
Sign In to View Organizational & Contract Pricing

Select a Size

50 μG

$774.00

$774.00

Check Cart for Availability
Request a Bulk Order

About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

recombinant

expressed in E. coli

Quality Level

100

mol wt

Mw 79 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (histone acetyltransferase (HAT))

NCBI accession no.

NM_003884.3

UniProt accession no.

Q92831

shipped in

dry ice

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
14-252-M14-249-M14-246-M
PCAF Protein, Active, 50 µg PCAF recombinant GST fusion protein, for use in Histone Acetyltransferase Assays. (HAT).

Sigma-Aldrich

14-309

PCAF Protein, Active, 50 µg

p38α/SAPK2a Protein, unactive, 50 µg

Sigma-Aldrich

14-252-M

p38α/SAPK2a Protein, unactive, 50 µg

p38δ/SAPK4 Protein, active, 10 µg Active, recombinant GST fusion protein fused to full length human p38δ/SAPK4. For use in Kinase Assays.

Sigma-Aldrich

14-249-M

p38δ/SAPK4 Protein, active, 10 µg

p38γ/SAPK3 Protein, active, 10 µg Active, recombinant GST fusion protein corresponding to full length human p38γ/SAPK3, for use in Kinase Assays.

Sigma-Aldrich

14-246-M

p38γ/SAPK3 Protein, active, 10 µg

recombinant

expressed in E. coli

recombinant

-

recombinant

expressed in E. coli

recombinant

expressed in E. coli

technique(s)

activity assay: suitable (histone acetyltransferase (HAT))

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

mol wt

Mw 79 kDa

mol wt

Mw 67.7 kDa

mol wt

Mw 71 kDa

mol wt

Mw 69 kDa

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

UniProt accession no.

Q92831

UniProt accession no.

Q16539

UniProt accession no.

O15264

UniProt accession no.

P30086

Quality Level

100

Quality Level

300

Quality Level

100

Quality Level

300

General description

Product Source: expressed in E. Coli corresponding to amino acids 352-832

Analysis Note

routinely evaluated by acetylation of core histones in vitro

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Prabhat Kumar Purbey et al.
Molecular and cellular biology, 29(5), 1321-1337 (2008-12-24)
Special AT-rich binding protein 1 (SATB1) acts as a global regulator of gene expression by recruiting various corepressor or coactivator complexes, thereby establishing a unique chromatin structure at its genomic targets in a context-dependent manner. Although SATB1 acts predominantly as
Matteo Savoia et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 4107-4123 (2018-12-12)
The epigenetic enzyme p300/CBP-associated factor (PCAF) belongs to the GCN5-related N-acetyltransferase (GNAT) family together with GCN5. Although its transcriptional and post-translational function is well characterized, little is known about its properties as regulator of cell metabolism. Here, we report the
Giosalba Burgio et al.
Journal of enzyme inhibition and medicinal chemistry, 31(sup3), 75-82 (2016-07-09)
Histones and polyamines are important determinants of the chromatin structure. Histones form the core of nucleosome particles and their modification by acetylation of N-terminal tails is involved in chromatin structural changes and transcriptional regulation. Polyamines, including spermidine, are also targets
R L Schiltz et al.
The Journal of biological chemistry, 274(3), 1189-1192 (1999-01-09)
A number of transcriptional coactivators possess intrinsic histone acetylase activity, providing a direct link between hyperacetylated chromatin and transcriptional activation. We have determined the core histone residues acetylated in vitro by recombinant p300 and PCAF within mononucleosomes. p300 specifically acetylates
Steven E Lang et al.
Oncogene, 22(18), 2836-2841 (2003-05-14)
The adenovirus E1A oncoprotein stimulates cell growth and inhibits differentiation by deregulating the normal transcription program via interaction with positive and negative cellular effectors. E1A associates with transcriptional regulatory complexes containing p400 and TRRAP involved in chromatin remodeling and decondensation.
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service