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14-550-M

Sigma-Aldrich

MAP Kinase 2/Erk2 Protein, active, Human, 10 µg

Active, N-terminal GST tagged, recombinant, full-length, human MAP Kinase 2/Erk2. Activated with MEK1 (Cat. # 14-429). For use in Kinase Assays.

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eCl@ss:
32160405
NACRES:
NA.41

biological source

human

Quality Level

recombinant

expressed in E. coli

mol wt

Mw 67.8 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

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This Item
14-173-M14-439-M14-515
recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in E. coli

mol wt

Mw 67.8 kDa

mol wt

Mw 67.8 kDa

mol wt

Mw 69.9 kDa

mol wt

Mw 70 kDa

manufacturer/tradename

Upstate®

manufacturer/tradename

Upstate®

manufacturer/tradename

Upstate®

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_002745.4, NM_138957.2

NCBI accession no.

NM_011949.3

NCBI accession no.

NM_002745.4, NM_138957.3

NCBI accession no.

NM_002745.4, NM_138957.2

General description

N-terminal GST tagged, recombinant, full-length, human MAP Kinase 2/Erk2, Activated with MEK1 (14-429).

Packaging

Also available in 125μg size, please inquire for pricing and availability.

Quality

Used to phosphorylate MBP (13-104)

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


Certificates of Analysis (COA)

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Yanping Li et al.
The Journal of biological chemistry, 288(38), 27646-27657 (2013-07-31)
The small G protein Ras regulates proliferation through activation of the mitogen-activated protein (MAP) kinase (ERK) cascade. The first step of Ras-dependent activation of ERK signaling is Ras binding to members of the Raf family of MAP kinase kinase kinases

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