171610

Anti-Amyloid Precursor Protein, C-Terminal (751-770) Rabbit pAb

liquid, Calbiochem^®

• Synonym(s): Anti-0443, Anti-APP-CT20

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• isotype: IgG
• shipped in: ambient
• storage temp.: −20°C

Description

General description

Anti-Amyloid Precursor Protein, C-Terminal (751-770), rabbit polyclonal, recognizes full-length APP and C-terminal soluble products CTFα, β, and γ. It is validated for WB, IF, IHC, and IP.

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes full-length APP and C-terminal soluble products CTFγ (~6 kDa), CTFα (~9 kDa), and CTFβ (~11 kDa).

Recognizes full-length APP and C-terminal soluble products CTFγ (~6 kDa), CTFα (~9 kDa), and CTFβ (~11 kDa).

Antibody Target Gene Symbol: APP

Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2

Entrez Gene Name: amyloid beta (A4) precursor protein

Hu Entrez ID: 351 (Related Antibodies: PC729, PC152,PC151, PC150, PC149, NE1012,171609, 171608, 171607, 171606, 171605, 171604, 171603, 171598, 171537)

Mu Entrez ID: 11820

Rat Entrez ID: 54226

Immunogen

Human

a synthetic peptide [(C)KMQQNGYENPTYKFFEQMQN] corresponding to amino acids 751-770 of human precursor protein (APP), conjugated to KLH

Application

Immunoblotting (1:5000-1:20,000)

Immunofluorescence (1:1000)

Immunohistochemistry (1:1000)

Immunoprecipitation (1:1000)

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Pinnix, I., et al. 2001. J. Biol. Chem.276, 481.

Variables associated with assay conditions will dictate the proper working dilution.

Legal Information

Purchase of this material is for research use only. Users are invited to request a license from Mayo prior to using the 0433 antibody or any derivatives for clinical diagnostic or therapeutic purposes. For license information, please contact: Mayo Medical Ventures, Office of Technology Commercialization (507) 284-8878, 200 First Street SW, Rochester, MN 55905-001.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable