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Sigma-Aldrich

Apicidin, Fusarium sp.

A potent, cell-permeable inhibitor of histone deacetylase (IC₅₀= 700 pM for parasitic histone deactetylase) that also exibits antiprotozoal and potential anti-malarial properties.

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Synonym(s):
Apicidin, Fusarium sp., cyclo-[L-(2-Amino-8-oxodecanoyl)-L-(N-methoxytryptophan)-L-isoleucyl-D-pipecolinyl], HDAC Inhibitor XI
Empirical Formula (Hill Notation):
C34H49N5O6
Molecular Weight:
623.78

Quality Level

Assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

DMSO: 50 mg/mL
ethanol: soluble

shipped in

ambient

storage temp.

−20°C

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Calpain Inhibitor VI The Calpain Inhibitor VI, also referenced under CAS 190274-53-4, controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

208745

Calpain Inhibitor VI

form

solid

form

solid

form

solid

form

lyophilized solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

OK to freeze, protect from light

color

white

color

white

color

colorless to white

color

white

solubility

DMSO: 50 mg/mL, ethanol: soluble

solubility

DMSO: 10 mg/mL

solubility

DMSO: 10 mg/mL

solubility

DMSO: 5 mg/mL

Biochem/physiol Actions

Cell permeable: yes
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Highly Toxic (H)

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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